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INTU Knockout Cell Lines

Gene: INTU

Official Full Name: inturned planar cell polarity proteinprovided by HGNC

Gene Summary: Predicted to enable phosphatidylinositol binding activity. Involved in embryonic digit morphogenesis; roof of mouth development; and tongue morphogenesis. Located in ciliary basal body and motile cilium. Implicated in asphyxiating thoracic dystrophy and orofaciodigital syndrome XVII. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27789 INTU Knockout cell line (HeLa) Human INTU 1:3~1:6 Negative Online Inquiry
KO27790 INTU Knockout cell line (HCT 116) Human INTU 1:2~1:4 Negative Online Inquiry
KO27791 INTU Knockout cell line (HEK293) Human INTU 1:3~1:6 Negative Online Inquiry
KO27792 INTU Knockout cell line (A549) Human INTU 1:3~1:4 Negative Online Inquiry

Background

INTU Gene Knockout Cell Lines are specially engineered cellular models that allow researchers to investigate the function of specific genes by selectively disrupting their expression. These cell lines are created using advanced CRISPR-Cas9 genome-editing technologies, which facilitate precise and efficient gene modifications. By introducing targeted mutations, INTU Gene Knockout Cell Lines enable scientists to elucidate the biological roles of genes in various cellular processes, thereby advancing our understanding of gene function and regulation in health and disease.

The core functionality of INTU Gene Knockout Cell Lines revolves around their ability to mimic a loss-of-function state of the targeted gene, making them invaluable tools in functional genomics. Upon knockout of a specific gene, researchers can observe resulting phenotypic changes, altered signaling pathways, and differences in cellular behavior. This allows for comprehensive studies in gene targeting, drug discovery, and the development of disease models.

From a scientific standpoint, these cell lines have broad applications in both research and clinical settings. They provide critical insights into gene-disease associations, potential therapeutic targets, and the mechanism of action of pharmaceuticals. Researchers leverage these models for high-throughput screening, investigating gene interactions, and validating drug candidates aimed at treating genetic disorders.

What sets INTU Gene Knockout Cell Lines apart from traditional knockout models is their uniformity, reproducibility, and ease of use. Furthermore, they come with verified off-target effects and characterization data, ensuring high-quality results. Researchers benefit from a streamlined workflow due to these ready-to-use cell lines, which significantly shortens the timeline from research idea to experimental validation.

In conclusion, INTU Gene Knockout Cell Lines are indispensable for researchers and clinicians aiming to explore gene function and develop novel therapies. Their superior design, robust performance, and detailed documentation make them a reliable choice for advancing scientific knowledge in genetics and molecular biology. At our company, we pride ourselves on delivering cutting-edge biological products backed by extensive expertise and commitment to supporting the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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