Gene: HPX
Official Full Name: hemopexinprovided by HGNC
Gene Summary: This gene encodes a plasma glycoprotein that binds heme with high affinity. The encoded protein is an acute phase protein that transports heme from the plasma to the liver and may be involved in protecting cells from oxidative stress. [provided by RefSeq, Apr 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO03771 | HPX Knockout cell line (HCT 116) | Human | HPX | 1:2~1:4 | Negative | Online Inquiry |
HPX Gene Knockout Cell Lines are genetically engineered mammalian cell lines that have been specifically designed to lack the expression of the hemopexin (HPX) gene. This product serves as a vital tool for researchers aiming to explore the role of HPX in various biological processes, including iron metabolism, inflammation, and cellular response to oxidative stress. By utilizing CRISPR-Cas9 technology, these cell lines are generated with precision, allowing researchers to investigate the downstream effects of HPX deficiency on cellular functions and disease models.
The key functionality of HPX Gene Knockout Cell Lines lies in their ability to simulate specific pathological states, enabling the study of iron homeostasis and its implications in diseases such as anemia and neurodegeneration. Without HPX, which plays a critical role in binding and transporting heme, cells can exhibit altered metabolic pathways and responses to stressors. This makes these cell lines an essential resource for elucidating mechanisms of disease and potential therapeutic targets.
In terms of scientific importance, HPX Gene Knockout Cell Lines can facilitate groundbreaking research in various fields, including hematology, neurobiology, and cell biology. Their applications extend to drug discovery, where understanding HPX’s actions can lead to the development of novel therapies targeting iron-related disorders and inflammatory conditions.
Compared to alternatives, HPX Gene Knockout Cell Lines offer the advantage of being thoroughly validated for the absence of the target gene, ensuring reproducibility and reliability in research outcomes. Additionally, their adaptability to various experimental conditions makes them versatile tools for both basic and applied research.
Researchers and clinicians can greatly benefit from these cell lines, as they provide a unique opportunity to dissect the complex roles of HPX in health and disease. The insights gained can pave the way for the development of innovative strategies for disease management and treatment.
As a company with extensive expertise in genetic engineering and molecular biology, we are committed to providing high-quality biological products that advance research and clinical practices. Our HPX Gene Knockout Cell Lines exemplify this dedication, offering researchers unparalleled resources to unlock the mysteries of gene function in health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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