Home / HPS5 Knockout Cell Lines

HPS5 Knockout Cell Lines

Gene: HPS5

Official Full Name: HPS5 biogenesis of lysosomal organelles complex 2 subunit 2provided by HGNC

Gene Summary: This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31049 HPS5 Knockout cell line (HeLa) Human HPS5 1:3~1:6 Negative Online Inquiry
KO31050 HPS5 Knockout cell line (HCT 116) Human HPS5 1:2~1:4 Negative Online Inquiry
KO31051 HPS5 Knockout cell line (HEK293) Human HPS5 1:3~1:6 Negative Online Inquiry
KO31052 HPS5 Knockout cell line (A549) Human HPS5 1:3~1:4 Negative Online Inquiry

Background

HPS5 Gene Knockout Cell Lines are precision-engineered cellular models that lack the expression of the HPS5 gene, a critical component involved in various cellular processes, including lysosomal function and protein trafficking. By utilizing advanced CRISPR-Cas9 technology, these cell lines facilitate the precise manipulation of genetic material, enabling researchers to investigate the multifaceted roles that HPS5 plays in disease pathways and cellular homeostasis.

The primary function of HPS5 Gene Knockout Cell Lines is to serve as a platform for understanding the biological implications of HPS5 deletion, particularly in conditions such as Hermansky-Pudlak syndrome and other lysosomal storage disorders. By observing cellular behavior in the absence of HPS5, researchers can elucidate the gene’s influence on cellular integrity, immune responses, and tissue homeostasis. These knockout models are invaluable in screening for drug candidates or elucidating the molecular mechanisms behind disease processes.

The scientific importance of HPS5 Gene Knockout Cell Lines extends beyond basic research; they also hold significant promise in translational medicine. Clinicians and researchers utilize these models to investigate potential therapeutic interventions targeting the pathways affected by HPS5 deficiencies. Moreover, their application in gene therapy research can lead to novel treatment strategies addressing a range of genetic disorders.

What distinguishes HPS5 Gene Knockout Cell Lines from alternative models is their specificity and reliability. Unlike other genetically modified lines, these cells provide well-characterized genetic backgrounds that enable reproducible results, thus enhancing the validity of experimental outcomes. Additionally, the knockout nature of these cells allows for a straightforward assessment of gene function, which can often be convoluted in wild-type cells.

In the competitive landscape of cell line development, our company stands out due to our commitment to quality and rigor in generating next-generation biological tools. With a team composed of expert molecular biologists and geneticists, we ensure that our HPS5 Gene Knockout Cell Lines are not only robust and thoroughly validated but also readily usable for a range of research applications. As such, we empower scientists and clinicians with the right tools to advance their understanding of HPS5 and its implications in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.