Gene: HEBP1
Official Full Name: heme binding protein 1provided by HGNC
Gene Summary: The full-length protein encoded by this gene is an intracellular tetrapyrrole-binding protein. This protein includes a natural chemoattractant peptide of 21 amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2 (FPRL2) and promotes calcium mobilization and chemotaxis in monocytes and dendritic cells. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23251 | HEBP1 Knockout cell line (HeLa) | Human | HEBP1 | 1:3~1:6 | Negative | Online Inquiry |
KO23252 | HEBP1 Knockout cell line (HCT 116) | Human | HEBP1 | 1:2~1:4 | Negative | Online Inquiry |
KO23253 | HEBP1 Knockout cell line (HEK293) | Human | HEBP1 | 1:3~1:6 | Negative | Online Inquiry |
KO23254 | HEBP1 Knockout cell line (A549) | Human | HEBP1 | 1:3~1:4 | Negative | Online Inquiry |
HEBP1 Gene Knockout Cell Lines are specialized cell models in which the HEBP1 gene has been intentionally disrupted through targeted gene editing techniques. This gene encodes the heme-binding protein 1, which plays a critical role in various cellular processes, including iron metabolism, oxidative stress response, and gene regulation. By generating knockout cell lines, researchers can elucidate the functional significance of HEBP1 and its involvement in specific biological pathways, providing insights into its potential role in diseases such as cancer and neurodegenerative disorders.
The key function of HEBP1 gene knockout cell lines lies in their ability to facilitate studies on gene function and regulation. The mechanism of action involves the complete loss of HEBP1 expression, enabling researchers to observe the resulting phenotypic changes. These models can be utilized to investigate the downstream effects of HEBP1 loss, particularly in cellular proliferation, apoptosis, and metabolic profiling. This understanding is vital for determining the implications of HEBP1 dysregulation in disease states and for developing targeted therapeutic interventions.
In the realm of both research and clinical applications, HEBP1 knockout cell lines present a valuable tool for studying gene-gene interactions and screening compounds that may restore normal function. Their use enhances the translation of basic research into clinical outcomes, particularly in drug development and precision medicine, thus holding significant promise for transforming therapeutic strategies.
Compared to traditional cell lines, HEBP1 gene knockout models provide a distinct advantage by offering a clearer understanding of the gene's specific role, thus reducing ambiguous findings related to gene expression variability. This specificity empowers researchers to derive robust conclusions and validate their hypotheses with greater confidence.
The value of HEBP1 Gene Knockout Cell Lines to researchers and clinicians is underscored by the ability to harness these tools for groundbreaking discoveries in gene function and therapeutic development. By utilizing these models, scientists can contribute significantly to the rapidly evolving landscape of molecular biology and genetics.
Our company specializes in the provision of high-quality biological products tailored for cutting-edge research applications. Our expertise in gene editing and cell line development ensures that researchers have reliable and innovative tools at their disposal to push the boundaries of scientific inquiry.
Please note that all services are for research use only. Not intended for any clinical use.
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