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HCFC2 Knockout Cell Lines

Gene: HCFC2

Official Full Name: host cell factor C2provided by HGNC

Gene Summary: This gene encodes one of two proteins which interact with VP16, a herpes simplex virus protein that initiates virus infection. Both the encoded protein and the original Herpes host cell factor interact with VP16 through a beta-propeller domain. The original Herpes host cell factor, however, is effective at initiating viral infection while the encoded protein is not. Transcripts of varying length due to alternative polyadenylation signals have been described. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26952 HCFC2 Knockout cell line (HeLa) Human HCFC2 1:3~1:6 Negative Online Inquiry
KO26953 HCFC2 Knockout cell line (HCT 116) Human HCFC2 1:2~1:4 Negative Online Inquiry
KO26954 HCFC2 Knockout cell line (HEK293) Human HCFC2 1:3~1:6 Negative Online Inquiry
KO26955 HCFC2 Knockout cell line (A549) Human HCFC2 1:3~1:4 Negative Online Inquiry

Background

HCFC2 Gene Knockout Cell Lines are specialized cellular models created through targeted genetic engineering to disrupt the Human Cyclin F-Associated Protein 2 (HCFC2) gene. This product is designed to facilitate the study of HCFC2's role in various biological processes, including cell cycle regulation, DNA repair mechanisms, and gene expression control. By knocking out the HCFC2 gene, these cell lines enable researchers to investigate the molecular pathways impacted by this crucial gene, making them valuable tools in both basic and applied biological research.

The primary mechanism of action for HCFC2 Gene Knockout Cell Lines relies on the specific deletion of the HCFC2 gene using CRISPR-Cas9 technology, which allows for precise edits to be made within the genome. This knockdown leads to observable phenotypic changes, facilitating research into the implications of HCFC2 deficiency in cellular proliferation and differentiation. The functional studies enabled by these cell lines can yield insights into the pathogenesis of various diseases, including tumors and genetic disorders.

From a scientific perspective, HCFC2 Gene Knockout Cell Lines have essential applications in research and clinical settings. They are instrumental in drug development, particularly for targeted therapies aimed at modulating HCFC2-related pathways. Additionally, these cell lines can aid in the screening of small molecules and biomolecules that impact HCFC2 function, allowing for the identification of potential therapeutic targets.

Unique advantages of HCFC2 Gene Knockout Cell Lines include their specificity and reliability compared to traditional cell models. These cell lines provide a consistent background for experimentation, minimizing variability and enhancing reproducibility in experimental outcomes. The precise genetic modification reduces off-target effects commonly seen with other gene editing techniques, which is crucial for researchers focused on translational applications.

For researchers and clinicians seeking reliable tools for gene function studies, the HCFC2 Gene Knockout Cell Lines are indispensable resources that promise to accelerate discoveries in genetic research, cancer biology, and therapeutic development. By providing a robust and innovative platform, [Your Company's Name] demonstrates its commitment to advancing biomedical research and enabling a deeper understanding of complex biological questions. With a track record of expertise in delivering cutting-edge biological products, we empower researchers worldwide to explore new frontiers in science.

Please note that all services are for research use only. Not intended for any clinical use.

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