Gene: GTPBP2
Official Full Name: GTP binding protein 2provided by HGNC
Gene Summary: GTP-binding proteins, or G proteins, constitute a superfamily capable of binding GTP or GDP. G proteins are activated by binding GTP and are inactivated by hydrolyzing GTP to GDP. This general mechanism enables G proteins to perform a wide range of biologic activities.[supplied by OMIM, Jan 2003]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21564 | GTPBP2 Knockout cell line (HeLa) | Human | GTPBP2 | 1:3~1:6 | Negative | Online Inquiry |
KO21565 | GTPBP2 Knockout cell line (HCT 116) | Human | GTPBP2 | 1:2~1:4 | Negative | Online Inquiry |
KO21566 | GTPBP2 Knockout cell line (HEK293) | Human | GTPBP2 | 1:3~1:6 | Negative | Online Inquiry |
KO21567 | GTPBP2 Knockout cell line (A549) | Human | GTPBP2 | 1:3~1:4 | Negative | Online Inquiry |
GTPBP2 Gene Knockout Cell Lines are genetically engineered cell lines that have had the GTPBP2 gene specifically inactivated or "knocked out." This product enables researchers to study the biological consequences of GTPBP2 gene deletion in a controlled environment. GTPBP2 plays a crucial role in nucleotide binding and is associated with various cellular processes, including translation initiation and ribosome biogenesis. The knockout of this gene serves as a powerful tool for dissecting its function and understanding its implications in cellular biology.
The primary function of GTPBP2 Gene Knockout Cell Lines lies in the investigation of ribosomal assembly and the intricate processes of gene expression regulation. By observing the cellular response pathways when GTPBP2 is absent, researchers can elucidate the mechanisms underlying diseases such as cancer and genetic disorders where protein synthesis is disrupted. These cell lines provide a relevant model for studying the role of ribonuclease activity, mitochondrial function, and signaling pathways, making them invaluable for applied research in cancer biology and therapeutic development.
In contrast to conventional knockdown methods that only reduce protein levels, complete knockout ensures a thorough understanding of GTPBP2's role, providing a more robust experimental framework. Moreover, the stability of these knockout cell lines allows for reproducible experimental outcomes and higher throughput in screening applications, addressing limitations associated with transient expression systems or incomplete knockdown models.
For researchers and clinicians, these cell lines represent an innovative tool for advancing therapeutic strategies and biological insights. The ability to study gene function with absolute specificity enhances the overall accuracy of experimental findings, ultimately contributing to the development of targeted therapies.
Our company specializes in providing high-quality, genetically modified cell lines that meet rigorous scientific standards. With a strong focus on innovation and a commitment to advancing research, we offer a comprehensive suite of biological products tailored to support the needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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