Gene: GREB1L
Official Full Name: GREB1 like retinoic acid receptor coactivatorprovided by HGNC
Gene Summary: Acts upstream of or within kidney development. Predicted to be located in membrane. Implicated in autosomal dominant nonsyndromic deafness 80 and renal agenesis. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26311 | GREB1L Knockout cell line (HeLa) | Human | GREB1L | 1:3~1:6 | Negative | Online Inquiry |
KO26312 | GREB1L Knockout cell line (HCT 116) | Human | GREB1L | 1:2~1:4 | Negative | Online Inquiry |
KO26313 | GREB1L Knockout cell line (HEK293) | Human | GREB1L | 1:3~1:6 | Negative | Online Inquiry |
KO26314 | GREB1L Knockout cell line (A549) | Human | GREB1L | 1:3~1:4 | Negative | Online Inquiry |
GREB1L Gene Knockout Cell Lines are specifically engineered cell lines in which the GREB1L gene has been inactivated through targeted gene knockout techniques. This innovative product enables researchers to explore the functional role of GREB1L in various biological processes such as transcription regulation, developmental biology, and the response to hormones. Through the precise alteration of the gene, these cell lines provide a robust platform for investigating the phenotypic consequences of GREB1L deficiency, thereby facilitating insights into disease mechanisms and potential therapeutic targets.
The key function of GREB1L Gene Knockout Cell Lines lies in their ability to model conditions where the GREB1L gene is absent. Mechanistically, this allows researchers to study downstream signaling pathways and phenotypic alterations, such as changes in cell growth, differentiation, or metabolic profiles, which can elucidate the gene's role in both normal physiology and pathological states. The use of CRISPR-Cas9 or other gene-editing technologies ensures a high specificity and efficiency in generating these knockout models, allowing for reproducibility in experimental designs.
In scientific research and clinical settings, GREB1L Gene Knockout Cell Lines are invaluable for drug discovery, functional genomics, and personalized medicine initiatives. Their applications extend to cancer research, where understanding gene interactions can lead to the identification of novel biomarkers and therapeutic strategies. Additionally, these cell lines can serve as a critical resource for studying hormonal signaling pathways, thereby impacting reproductive health research and beyond.
One of the significant advantages of GREB1L Gene Knockout Cell Lines is their robustness and reliability compared to other alternatives, such as transient knockdown models. Permanent knockouts provide stable genetic modifications, ensuring that experimental results are consistent and reproducible over extended periods. This permanence enables long-term studies and decreases the variability often encountered with transient methods.
These gene knockout cell lines represent a transformative tool for investigators looking to delve deep into the roles of specific genes and their implications in health and disease. By employing GREB1L Gene Knockout Cell Lines, researchers gain access to a specialized product that not only streamlines experimental workflows but also enhances the precision of scientific inquiry.
With a commitment to delivering high-quality biological tools, our company has established itself as a leader in the field of genetic engineering. We provide researchers with a comprehensive suite of products, including knockout cell lines, that are supported by our extensive expertise and innovation in biotechnology.
Please note that all services are for research use only. Not intended for any clinical use.
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