Gene: GRAMD1C
Official Full Name: GRAM domain containing 1Cprovided by HGNC
Gene Summary: Predicted to enable cholesterol binding activity and cholesterol transfer activity. Predicted to be involved in cellular response to cholesterol and intracellular sterol transport. Predicted to be located in endoplasmic reticulum; membrane; and organelle membrane contact site. Predicted to be active in endoplasmic reticulum membrane; endoplasmic reticulum-plasma membrane contact site; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17266 | GRAMD1C Knockout cell line (HeLa) | Human | GRAMD1C | 1:3~1:6 | Negative | Online Inquiry |
KO17267 | GRAMD1C Knockout cell line (HCT 116) | Human | GRAMD1C | 1:2~1:4 | Negative | Online Inquiry |
KO17268 | GRAMD1C Knockout cell line (A549) | Human | GRAMD1C | 1:3~1:4 | Negative | Online Inquiry |
GRAMD1C Gene Knockout Cell Lines are genetically engineered cell lines that have had the GRAMD1C gene excised or inactivated. This product is designed to facilitate the study of the GRAMD1C gene's role in various biological processes, particularly those related to lipid metabolism, cell signaling, and membrane dynamics. By creating models that lack the GRAMD1C gene, researchers can investigate the downstream effects of its absence, enabling a deeper understanding of its contributions to cellular functions and disease mechanisms.
The key function of GRAMD1C gene knockout cell lines lies in their ability to serve as a tool for functional genomics and cellular biology. When GRAMD1C is knocked out, the changes in physiological processes, such as lipid transfer and cellular response to stress, can be observed and analyzed. The mechanism of action primarily revolves around the role of GRAMD1C in regulating membrane lipid composition and its interactions with other cellular pathways. Researchers can utilize these cell lines to delineate the pathway influences of GRAMD1C, making it indispensable in both basic biology and translational research.
The scientific importance of GRAMD1C gene knockout cell lines extends to various applications in research and clinical settings. They are particularly relevant in studies concerning metabolic disorders, cancers, and neurodegenerative diseases, where the understanding of lipid homeostasis is pivotal. The insights gained from these models can lead to the identification of therapeutic targets and novel intervention strategies.
What sets GRAMD1C gene knockout cell lines apart from alternatives is their specificity and precision. Designed under stringent protocols, these cell lines ensure high efficiency in gene knockout and reproducibility in experimental results. Additionally, researchers can save valuable time and resources by utilizing ready-to-use cell lines rather than attempting to create their own knockouts from scratch, thus accelerating the pace of discovery.
For researchers and clinicians, the ability to manipulate and understand cellular functions at the genetic level is invaluable. GRAMD1C gene knockout cell lines provide critical insights that can lead to significant advancements in cell biology and disease understanding, proving to be an essential asset in the modern research landscape.
Our company specializes in the production of advanced biological research tools, leveraging years of expertise in genetic engineering and cell line development. We are committed to providing high-quality, innovative products that empower researchers to push the boundaries of scientific knowledge.
Please note that all services are for research use only. Not intended for any clinical use.
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