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GNB5 Knockout Cell Lines

Gene: GNB5

Official Full Name: G protein subunit beta 5provided by HGNC

Gene Summary: Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternatively spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO10334 GNB5 Knockout cell line (HeLa) Human GNB5 1:3~1:6 Negative Online Inquiry
KO10335 GNB5 Knockout cell line (HCT 116) Human GNB5 1:2~1:4 Negative Online Inquiry
KO10336 GNB5 Knockout cell line (HEK293) Human GNB5 1:3~1:6 Negative Online Inquiry
KO10337 GNB5 Knockout cell line (A549) Human GNB5 1:3~1:4 Negative Online Inquiry

Background

GNB5 Gene Knockout Cell Lines are advanced biological products specially designed to facilitate in-depth research into the GNB5 gene's role in cellular processes. GNB5, part of the G protein-coupled receptor signaling pathway, is crucial for a variety of physiological functions, including signal transduction and cellular communication. By using these knockout cell lines, researchers can eliminate GNB5 expression, allowing for direct observation of cellular changes resulting from this genetic modification.

These cell lines function by employing CRISPR-Cas9 technology to induce targeted deletions of the GNB5 gene, effectively generating a model system where the impacts of its absence can be precisely assessed. This mechanism enables researchers to dissect the pathway's contribution to various signaling cascades and understand the broader implications of GNB5 in pathophysiological conditions such as cardiovascular diseases and cancer.

The scientific significance of GNB5 Gene Knockout Cell Lines extends into numerous research and clinical applications, where they serve as pivotal tools for understanding drug mechanisms, evaluating the efficacy of new therapeutic agents, and unraveling genetic contributors to disease. Researchers in pharmacology, genetics, and cellular biology will find these cell lines invaluable for hypothesis-driven studies and screening assays.

Compared to other gene knockout models, GNB5 Gene Knockout Cell Lines offer enhanced specificity and reproducibility. The utilization of CRISPR technology not only ensures a clean deletion of the gene but also allows for rapid generation of stable cell lines. This positions our product as a superior choice for researchers seeking reliable and efficient genetic models without the off-target effects that often accompany other methods.

Investing in GNB5 Gene Knockout Cell Lines means equipping your laboratory with a groundbreaking resource that enhances your research capabilities. These cell lines provide the invaluable opportunity to produce data that can lead to significant scientific advancements and clinically relevant insights. Our company specializes in developing cutting-edge biological products backed by rigorous research and a commitment to quality, ensuring that you receive only the best tools to drive your discoveries forward.

Please note that all services are for research use only. Not intended for any clinical use.

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