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GLDN Knockout Cell Lines

Gene: GLDN

Official Full Name: gliomedinprovided by HGNC

Gene Summary: This gene encodes a protein that contains olfactomedin-like and collagen-like domains. The encoded protein, which exists in both transmembrane and secreted forms, promotes formation of the nodes of Ranvier in the peripheral nervous system. Mutations in this gene cause a form of lethal congenital contracture syndrome in human patients. Autoantibodies to the encoded protein have been identified in sera form patients with multifocal motor neuropathy. [provided by RefSeq, May 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17368 GLDN Knockout cell line (HCT 116) Human GLDN 1:2~1:4 Negative Online Inquiry

Background

GLDN Gene Knockout Cell Lines are genetically engineered cellular models designed to facilitate the study of gene function and expression through targeted gene disruption. Created using advanced CRISPR/Cas9 technology, these knockout cell lines allow researchers to specifically deactivate the GLDN gene, enabling a deeper understanding of its role in various biological processes and pathways.

The key function of these cell lines lies in their ability to replicate the physiological conditions of the human body while enabling the comparative analysis of cellular mechanisms. By knocking out the GLDN gene, researchers can observe downstream effects on gene expression, protein activity, and cellular behavior. This process is crucial for elucidating the biological roles of GLDN, which is implicated in neurological functions and may play a role in certain diseases.

The scientific importance of GLDN Gene Knockout Cell Lines is highlighted by their wide-ranging applications in both research and clinical settings. They can be utilized in drug discovery to screen potential therapeutic compounds, in toxicity studies, or for studying gene therapies aimed at restoring normal function in disease models. Their use can significantly advance our understanding of genetic disorders and facilitate the development of novel treatment strategies.

Compared to traditional knockout models, our GLDN Gene Knockout Cell Lines offer higher precision in gene editing and a rapid turnaround in cell line generation. This is coupled with robust characterization, ensuring consistent phenotypic and genotypic outcomes. These advantages make them a preferred choice over competitors’ offerings, which may involve more cumbersome processes that can introduce variability and delay research timelines.

The value of GLDN Gene Knockout Cell Lines extends beyond individual research objectives; they empower researchers and clinicians to translate fundamental scientific discoveries into actionable insights, ultimately enhancing patient care and treatment efficacy. As a leader in the development of high-quality biological products, our company is dedicated to supporting the scientific community with innovative tools that drive research forward. Through our expertise, we ensure that each product not only meets but exceeds the rigorous demands of modern biological research.

Please note that all services are for research use only. Not intended for any clinical use.

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