Gene: GGACT
Official Full Name: gamma-glutamylamine cyclotransferaseprovided by HGNC
Gene Summary: The protein encoded by this gene aids in the proteolytic degradation of crosslinked fibrin by breaking down isodipeptide L-gamma-glutamyl-L-epsilon-lysine, a byproduct of fibrin degradation. The reaction catalyzed by the encoded gamma-glutamylaminecyclotransferase produces 5-oxo-L-proline and a free alkylamine. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Aug 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24077 | GGACT Knockout cell line (HeLa) | Human | GGACT | 1:3~1:6 | Negative | Online Inquiry |
KO24078 | GGACT Knockout cell line (HCT 116) | Human | GGACT | 1:2~1:4 | Negative | Online Inquiry |
KO24079 | GGACT Knockout cell line (HEK293) | Human | GGACT | 1:3~1:6 | Negative | Online Inquiry |
KO24080 | GGACT Knockout cell line (A549) | Human | GGACT | 1:3~1:4 | Negative | Online Inquiry |
GGACT Gene Knockout Cell Lines are advanced biological models created through precise genome editing techniques, primarily CRISPR-Cas9, to effectively eliminate specific gene functions in various cell types. These knockout cell lines serve as invaluable tools for functional genomics, allowing researchers to dissect gene roles in fundamental biological processes, disease mechanisms, and drug responses.
The primary function of GGACT Gene Knockout Cell Lines lies in their ability to provide a controlled environment in which researchers can explore the impacts of gene loss on cellular behavior. By knocking out targeted genes, scientists can study downstream effects on pathways, protein interactions, and phenotypic outcomes, facilitating a deeper understanding of gene function and its relevance to health and disease. These cell lines also enable the assessment of potential therapeutic targets and enhance the development of new treatments by simulating disease states at a cellular level.
The scientific importance of GGACT Gene Knockout Cell Lines extends to both research and clinical settings. They are essential for studying genetic diseases, cancer biology, and the mechanisms of drug resistance. In a clinical context, these models can be used to predict patient responses to treatments and to investigate novel gene therapy approaches, ultimately contributing to personalized medicine.
One key advantage of GGACT Gene Knockout Cell Lines is their robustness and reproducibility. Unlike traditional knockout models, which can be time-consuming and resource-intensive, our cell lines are readily available, allowing for immediate experimentation. Furthermore, they come with extensive validation data, ensuring the reliability of experimental outcomes. This facilitates a higher throughput of research and accelerates the pace of discovery.
For researchers and clinicians, the value of GGACT Gene Knockout Cell Lines lies in their ability to offer rapid and reliable insights into gene function, providing a competitive edge in the fast-evolving fields of genomics and molecular biology. Our commitment to quality and innovation is underpinned by a team of experts with extensive experience in genetic engineering and product development, ensuring that our offerings consistently meet the highest scientific standards and user requirements.
Please note that all services are for research use only. Not intended for any clinical use.
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