Gene: GCNA
Official Full Name: germ cell nuclear acidic peptidaseprovided by HGNC
Gene Summary: Enables SUMO polymer binding activity. Involved in protein-DNA covalent cross-linking repair. Located in PML body. Implicated in X-linked spermatogenic failure 4. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22112 | GCNA Knockout cell line (HeLa) | Human | GCNA | 1:3~1:6 | Negative | Online Inquiry |
KO22113 | GCNA Knockout cell line (HCT 116) | Human | GCNA | 1:2~1:4 | Negative | Online Inquiry |
KO22114 | GCNA Knockout cell line (HEK293) | Human | GCNA | 1:3~1:6 | Negative | Online Inquiry |
KO22115 | GCNA Knockout cell line (A549) | Human | GCNA | 1:3~1:4 | Negative | Online Inquiry |
GCNA Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to eliminate the expression of the GCNA gene, which encodes a protein essential for crucial cellular processes, including cell proliferation and differentiation. By utilizing CRISPR-Cas9 technology, these knockout cell lines provide researchers with an invaluable tool to study the role of the GCNA gene in various biological contexts and disease mechanisms.
The key function of the GCNA Gene Knockout Cell Lines is to serve as a model for gene function analysis, enabling scientists to investigate how the absence of the GCNA gene affects cellular behavior, signaling pathways, and gene expression profiles. With the knockout model in place, researchers can conduct experiments to elucidate the gene's contributions to critical phenomena such as tumorigenesis, immune response modulation, and cellular stress reactions.
The scientific importance of these cell lines extends into multiple research domains, including cancer biology, developmental biology, and regenerative medicine. In clinical settings, understanding the role of GCNA may lead to novel therapeutic targets, facilitating the development of innovative treatment strategies against diseases linked to dysregulation of the GCNA gene.
One of the unique selling points of the GCNA Gene Knockout Cell Lines is their reliability and specificity, achieved through precise gene editing methods. Conventional gene knockdown approaches, such as RNA interference, often result in incomplete inhibition of gene expression and off-target effects. In contrast, the GCNA knockout cells deliver a definitive and stable loss of function, providing clearer insights into gene function and pathway analysis.
Researchers and clinicians will find the GCNA Gene Knockout Cell Lines to be an indispensable resource for advancing their work. The ability to analyze the direct implications of GCNA in various biological processes enables researchers to generate robust data that can lead to breakthroughs in understanding and treatment of diseases.
Our company specializes in the development of cutting-edge biological products, backed by years of expertise in genetic engineering and cell line development. We are committed to providing researchers and healthcare professionals with innovative tools that enhance their capabilities in scientific exploration and clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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