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GATAD1 Knockout Cell Lines

Gene: GATAD1

Official Full Name: GATA zinc finger domain containing 1provided by HGNC

Gene Summary: The protein encoded by this gene contains a zinc finger at the N-terminus, and is thought to bind to a histone modification site that regulates gene expression. Mutations in this gene have been associated with autosomal recessive dilated cardiomyopathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09568 GATAD1 Knockout cell line (HeLa) Human GATAD1 1:3~1:6 Negative Online Inquiry
KO09569 GATAD1 Knockout cell line (HCT 116) Human GATAD1 1:2~1:4 Negative Online Inquiry
KO09570 GATAD1 Knockout cell line (HEK293) Human GATAD1 1:3~1:6 Negative Online Inquiry
KO09571 GATAD1 Knockout cell line (A549) Human GATAD1 1:3~1:4 Negative Online Inquiry

Background

GATAD1 Gene Knockout Cell Lines are meticulously engineered cellular models specifically designed to facilitate the in-depth study of the GATAD1 gene's functions and its implications in various biological pathways. GATAD1 encodes a protein involved in critical processes such as chromatin remodeling and transcriptional regulation, making these knockout models essential for understanding its role in cellular biology.

The primary mechanism of these cell lines involves targeted gene disruption using advanced CRISPR/Cas9 technology, leading to the complete knockout of the GATAD1 gene. As a result, researchers can observe the phenotypic consequences of GATAD1 ablation, unraveling its contributions to cellular processes such as differentiation, apoptosis, and response to stressors. This enables researchers to elucidate the molecular mechanisms underlying diseases related to GATAD1 dysregulation, including certain cancers and neurodegenerative disorders.

The scientific significance of GATAD1 Gene Knockout Cell Lines extends to various research fields, including cancer biology, neurology, and gene therapy. These models are pivotal when investigating therapeutic targets and drug responses, as they enable researchers to correlate the absence of GATAD1 with altered cellular behaviors, thereby accelerating the development of innovative treatment strategies.

A unique selling point of GATAD1 Gene Knockout Cell Lines is their high specificity and reliability compared to alternatives like transient transfection or traditional knockout methods, which can yield heterogeneous results. Our cell lines come with validated phenotypic characterization and extensive documentation, providing a robust platform for reproducible research.

By utilizing GATAD1 Gene Knockout Cell Lines, researchers and clinicians gain access to a powerful tool for dissecting gene function and model systems in human biology. Our commitment to excellence in genetic engineering and adherence to regulatory standards ensures that you receive products of the highest quality tailored for cutting-edge scientific inquiries.

Please note that all services are for research use only. Not intended for any clinical use.

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