Gene: GAS7
Official Full Name: growth arrest specific 7provided by HGNC
Gene Summary: Growth arrest-specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal development. Several transcript variants encoding proteins which vary in the N-terminus have been described. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34087 | GAS7 Knockout cell line (HeLa) | Human | GAS7 | 1:3~1:6 | Negative | Online Inquiry |
KO34088 | GAS7 Knockout cell line (HCT 116) | Human | GAS7 | 1:2~1:4 | Negative | Online Inquiry |
KO34089 | GAS7 Knockout cell line (HEK293) | Human | GAS7 | 1:3~1:6 | Negative | Online Inquiry |
KO34090 | GAS7 Knockout cell line (A549) | Human | GAS7 | 1:3~1:4 | Negative | Online Inquiry |
GAS7 Gene Knockout Cell Lines are specially engineered cell lines in which the Growth Arrest-Specific 7 (GAS7) gene has been thoroughly disrupted, enabling the study of its functional roles in cellular mechanisms and disease pathology. By employing targeted gene-editing technologies, such as CRISPR-Cas9, these cell lines lack the GAS7 protein, allowing researchers to investigate the gene’s contributions to processes including cell proliferation, apoptosis, and differentiation, particularly in relation to cancer and neurodevelopmental disorders.
The key mechanism underlying the functionality of GAS7 Gene Knockout Cell Lines is the complete absence of the GAS7 protein, which has been shown to influence several signaling pathways associated with cellular growth and behavior. This knockout model can elucidate the gene's role in tumor suppression, as well as how alterations in GAS7 expression may contribute to various diseases. Such insights are particularly valuable in translational research and drug discovery, where understanding the molecular underpinnings of disease is crucial.
The scientific significance of these cell lines extends across various applications, from basic research to clinical investigations. They provide a unique platform for evaluating the effects of potential therapeutics targeting GAS7-related pathways, thus facilitating advancements in personalized medicine. Moreover, GAS7 Gene Knockout Cell Lines offer researchers a reliable, reproducible model that parallels the in vivo environment more closely than conventional cell lines.
The primary advantages of GAS7 Gene Knockout Cell Lines over alternatives lie in their specificity and precision. While typical knockdown models may yield variable levels of residual expression, our knockout lines ensure complete gene disruption, enabling clearer interpretations of experimental results. This specificity enhances the reliability of data, significantly reducing the potential for confounding variables, and thus provides a robust means for hypothesis testing.
For researchers and clinicians addressing complex biological questions involving GAS7, our cell lines present a powerful tool that enhances experimental rigor and opens avenues for innovative therapeutic strategies. With a commitment to advancing scientific research, our company leverages cutting-edge technology and expertise, ensuring that our GAS7 Gene Knockout Cell Lines meet the highest standards of quality and performance for your research needs.
Please note that all services are for research use only. Not intended for any clinical use.
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