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FOXC1 Knockout Cell Lines

Gene: FOXC1

Official Full Name: forkhead box C1provided by HGNC

Gene Summary: This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03285 FOXC1 Knockout cell line (HeLa) Human FOXC1 1:3~1:6 Negative Online Inquiry
KO03286 FOXC1 Knockout cell line (HCT 116) Human FOXC1 1:2~1:4 Negative Online Inquiry
KO03287 FOXC1 Knockout cell line (HEK293) Human FOXC1 1:3~1:6 Negative Online Inquiry
KO03288 FOXC1 Knockout cell line (A549) Human FOXC1 1:3~1:4 Negative Online Inquiry

Background

FOXC1 Gene Knockout Cell Lines are a cutting-edge research tool specifically designed to facilitate the study of the FOXC1 gene, a critical regulator in various biological processes, including cellular differentiation and immune responses. These cell lines allow for the targeted disruption of the FOXC1 gene, enabling researchers to investigate its function, role in disease pathology, and potential therapeutic interventions in a controlled laboratory setting.

The principal mechanism behind the FOXC1 Gene Knockout Cell Lines relies on CRISPR-Cas9 technology, a precise and efficient gene-editing tool that introduces specific mutations into the FOXC1 gene. By creating a knockout of this gene, scientists can analyze the subsequent phenotypic and molecular changes within the cell, shedding light on the gene’s involvement in developmental pathways and its contribution to diseases such as cancer and ocular disorders.

From a scientific perspective, these cell lines hold substantial importance in both research and clinical applications. They provide a robust platform for investigating FOXC1’s role in tumorigenesis, the progression of ocular diseases, and the immune response. Such investigations are critical for developing targeted therapies and understanding the underlying mechanisms of diseases linked to FOXC1 dysregulation.

Compared to alternative methods, FOXC1 Gene Knockout Cell Lines present significant advantages, including high specificity of gene editing, reproducibility across multiple experiments, and a streamlined process for functional analyses. Furthermore, these cell lines offer adaptable solutions tailored to various experimental needs, enabling researchers to customize their investigations according to distinct research objectives.

Overall, FOXC1 Gene Knockout Cell Lines represent an invaluable asset for researchers and clinicians aiming to deepen their understanding of gene function in human health and disease. These innovative tools not only expedite scientific discovery but also hold promise in translating findings into clinical applications. Our company prides itself on its expertise in developing high-quality biological research tools, ensuring that our customers have access to the best resources available for advancing their research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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