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FNDC5 Knockout Cell Lines

Gene: FNDC5

Official Full Name: fibronectin type III domain containing 5provided by HGNC

Gene Summary: This gene encodes a secreted protein that is released from muscle cells during exercise. The encoded protein may participate in the development of brown fat. Translation of the precursor protein initiates at a non-AUG start codon at a position that is conserved as an AUG start codon in other organisms. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07056 FNDC5 Knockout cell line (A549) Human FNDC5 1:3~1:4 Negative Online Inquiry

Background

FNDC5 Gene Knockout Cell Lines are advanced biological constructs engineered to facilitate the study of the fibronectin type III domain-containing protein 5 (FNDC5), a crucial player in metabolic regulation and adipogenesis. These cell lines are created through targeted gene editing techniques, such as CRISPR-Cas9, to effectively delete the FNDC5 gene, allowing researchers to observe the resultant physiological and biochemical changes that arise from the absence of this protein.

The primary function of FNDC5 includes its involvement in the synthesis of irisin, a hormone linked to energy expenditure and thermogenesis. By utilizing FNDC5 Gene Knockout Cell Lines, scientists can elucidate the mechanisms by which FNDC5 influences metabolic pathways, adipose tissue remodeling, and intercellular signaling. This provides a clearer understanding of disorders such as obesity and type 2 diabetes, paving the way for innovative therapeutic strategies.

The scientific importance of these cell lines is substantial, particularly in both research and clinical applications. They allow for the exploration of FNDC5's role in cellular processes, including differentiation, liver function, and muscle metabolism. With the increasing prevalence of metabolic diseases, these cell lines serve as a critical tool for developing novel interventions and medications targeted at ameliorating these conditions.

What sets our FNDC5 Gene Knockout Cell Lines apart from alternatives is their high specificity and reliability, ensuring reproducible results across various experimental setups. Furthermore, our products are rigorously tested for quality and confirmed through extensive characterization to uphold the highest standards in scientific research.

Researchers and clinicians will find significant value in these cell lines, as they provide a unique opportunity to dissect the intricacies of metabolic regulation with precision. Our commitment to advancing biological research positions us as a trusted source of innovative products, underpinned by a breadth of expertise in cellular biology and genetic engineering. By choosing our FNDC5 Gene Knockout Cell Lines, users can confidently advance their investigations in metabolic health, leading to impactful discoveries in biomedical science.

Please note that all services are for research use only. Not intended for any clinical use.

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