Gene: FGF9
Official Full Name: fibroblast growth factor 9provided by HGNC
Gene Summary: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO10794 | FGF9 Knockout cell line (HCT 116) | Human | FGF9 | 1:2~1:4 | Negative | Online Inquiry |
KO10795 | FGF9 Knockout cell line (HEK293) | Human | FGF9 | 1:3~1:6 | Negative | Online Inquiry |
FGF9 Gene Knockout Cell Lines are advanced biological tools developed for the targeted study of fibroblast growth factor 9 (FGF9) and its role in cellular processes. These cell lines have been genetically engineered to disrupt the FGF9 gene, enabling researchers to examine the consequences of its absence on cell behavior, signaling pathways, and physiological functions.
The key mechanism behind these knockout cell lines involves CRISPR-Cas9 technology, which allows precise editing of the genome. By creating a specific mutation in the FGF9 gene, these cell lines offer a streamlined approach to investigating the downstream effects on growth factor signaling and related biological processes. Researchers can utilize these knockout cell lines to elucidate FGF9's role in development, cancer progression, and tissue regeneration, significantly enhancing our understanding of various disease states and biological pathways.
From a scientific perspective, FGF9 is recognized for its involvement in critical processes such as mesoderm and gonadal development. By employing FGF9 Gene Knockout Cell Lines, researchers can engage in translational research that is pivotal for therapeutic advancements, including regenerative medicine and cancer therapies. These cell lines serve not only as vital tools for basic research but also facilitate the development of targeted treatments by providing insights into FGF9's biological functions.
Unlike traditional methods that may not provide a comprehensive picture of gene function, our FGF9 knockout cell lines offer a unique advantage by allowing for consistent, reproducible results. This specificity makes them invaluable for researchers seeking to delineate the role of FGF9 in various contexts, elevating their research to new levels of precision.
In an era where gene function understanding is paramount, our FGF9 Gene Knockout Cell Lines stand out for their tailored approach and extensive application potential. As a company specialized in the development of high-quality biological products, we are committed to empowering researchers and clinicians with innovative solutions that drive scientific discovery and enhance therapeutic outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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