Home / FGF13 Knockout Cell Lines

FGF13 Knockout Cell Lines

Gene: FGF13

Official Full Name: fibroblast growth factor 13provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked cognitive disability mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini. [provided by RefSeq, Nov 2008]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01026 FGF13 Knockout cell line (HEK293) Human FGF13 1:3~1:6 Negative Online Inquiry

Background

FGF13 Gene Knockout Cell Lines are specially engineered cellular models in which the FGF13 gene has been inactivated, enabling researchers to study the gene's functions and contributions to various biological processes. FGF13, or Fibroblast Growth Factor 13, plays a pivotal role in cellular signaling, particularly in cardiac and neuronal tissues. By utilizing these knockout cell lines, scientists can analyze the downstream effects of FGF13 loss, leading to a better understanding of its roles in cell differentiation, proliferation, and survival.

The primary mechanism by which FGF13 influences cellular behavior involves modulating intracellular signaling pathways associated with growth factor receptors and ion channels. When FGF13 is functionally absent, it can lead to alterations in cell cycle regulation, apoptosis, and even the pathophysiology of diseases such as cardiac hypertrophy and neurodegenerative disorders. Thus, these knockout cell lines serve as vital tools for elucidating disease mechanisms and identifying potential therapeutic targets.

In the realm of scientific research, FGF13 Gene Knockout Cell Lines hold significant importance for both experimental validation and translational applications. By providing a simplified model to study loss-of-function scenarios, researchers can efficiently screen drug compounds, explore genetic interactions, and investigate cellular responses to various stimuli in a controlled environment.

Compared to traditional wild-type models, these knockout cell lines offer specific advantages, such as consistent reproducibility, streamlined experimental design, and the elimination of confounding variables attributable to FGF13 activity. This precision allows for more reliable data interpretation and enhanced clarity in research findings.

For researchers, clinicians, and biotechnology professionals, the utility of FGF13 Gene Knockout Cell Lines is evident in their ability to facilitate novel discoveries that can contribute to the advancement of personalized medicine and targeted therapies.

Our company is dedicated to providing high-quality biological products that empower scientific inquiry. With our expertise and commitment to innovation, we ensure that our customers have access to cutting-edge tools for their research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.