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FCRLB Knockout Cell Lines

Gene: FCRLB

Official Full Name: Fc receptor like Bprovided by HGNC

Gene Summary: FCRL2 belongs to the Fc receptor family. Fc receptors are involved in phagocytosis, antibody-dependent cell cytotoxicity, immediate hypersensitivity, and transcytosis of immunoglobulins via their ability to bind immunoglobulin (Ig) constant regions (Chikaev et al., 2005 [PubMed 15676285]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26800 FCRLB Knockout cell line (HCT 116) Human FCRLB 1:2~1:4 Negative Online Inquiry

Background

FCRLB Gene Knockout Cell Lines represent a significant advancement in the field of genetic research and therapeutic development, serving as engineered cell lines where the FCRLB gene has been effectively disrupted through targeted genome editing techniques such as CRISPR-Cas9. This product enables researchers to investigate the functional roles of the FCRLB gene, which is implicated in various immune responses, including antibody regulation and the modulation of inflammation. By utilizing these knockout cell lines, scientists can elucidate the cellular pathways influenced by FCRLB, enhancing the understanding of its contribution to pathology in certain autoimmune disorders and cancers.

The primary mechanism by which FCRLB knockout influences cellular behavior involves the alteration of intracellular signaling cascades that are typically mediated by the FCRLB protein. By generating these specific cell lines, researchers can study phenotypic changes resulting from this genetic manipulation, including distinctions in cytokine production, cellular proliferation, and response to immunotherapies. This functional understanding fosters the development of novel therapeutic interventions aimed at modulating immune responses in diseases where FCRLB is shown to play a critical role.

One of the key advantages of FCRLB Gene Knockout Cell Lines is their precision and specificity. Unlike alternative models that may introduce off-target effects or do not adequately replicate the specific genetic background of human pathologies, these knockout lines provide a clear and focused approach to studying the direct impact of FCRLB gene absence. Additionally, they enable high-throughput screening applications, making them particularly valuable for drug development processes.

Researchers and clinicians find immense value in utilizing FCRLB Gene Knockout Cell Lines because they not only streamline the investigation of gene function but also contribute to the overarching goal of personalized medicine by paving the way for tailored therapeutic strategies. Our expertise in genetic engineering and commitment to providing cutting-edge biological products ensure that our cell lines are rigorously validated and optimized for a variety of applications. By choosing our FCRLB Gene Knockout Cell Lines, users are empowered with tools that will enhance their research and clinical outcomes significantly.

Please note that all services are for research use only. Not intended for any clinical use.

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