Gene: FAT4
Official Full Name: FAT atypical cadherin 4provided by HGNC
Gene Summary: The protein encoded by this gene is a member of the protocadherin family. This gene may play a role in regulating planar cell polarity (PCP). Studies in mice suggest that loss of PCP signaling may cause cystic kidney disease, and mutations in this gene have been associated with Van Maldergem Syndrome 2. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Mar 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20643 | FAT4 Knockout cell line (HeLa) | Human | FAT4 | 1:3~1:6 | Negative | Online Inquiry |
KO20644 | FAT4 Knockout cell line (HEK293) | Human | FAT4 | 1:3~1:6 | Negative | Online Inquiry |
KO39174 | fat4 Knockout cell line (A549) | Human | FAT4 | 1:3~1:4 | Negative | Online Inquiry |
FAT4 Gene Knockout Cell Lines represent a cutting-edge tool in genetic research, specifically designed to enable the functional characterization of the FAT4 gene, a crucial component involved in cell signaling pathways and tissue development. These engineered cell lines have been meticulously created using CRISPR/Cas9 technology to delete or disrupt the FAT4 gene, providing researchers with an invaluable resource for studying gene function, protein interactions, and associated phenotypic outcomes.
The key function of FAT4 Gene Knockout Cell Lines lies in their ability to allow the precise investigation of the FAT4 gene's role in cellular processes. By examining these cell lines, researchers can elucidate the mechanisms by which FAT4 influences cellular behavior, including its contributions to tissue morphogenesis, polarity, and pathways relevant to various diseases such as cancer. The knockout approach also facilitates the assessment of compensatory mechanisms that might arise from the absence of FAT4, thereby enriching the understanding of complex biological systems.
Scientifically, these cell lines are pivotal for both researchers and clinicians seeking to explore the pathological relevance of the FAT4 gene. Applications extend to basic science research, drug discovery, and the development of novel therapeutic strategies. Their utility in high-throughput screening makes them particularly attractive for pharmacological studies aimed at modulating cellular outcomes based on FAT4-determined signaling.
In comparison to traditional knockout models, FAT4 Gene Knockout Cell Lines offer distinct advantages, including reduced variability, enhanced reproducibility, and a faster turnaround time for experimental results. Furthermore, these cell lines can be readily adapted for various assays, including gene expression analysis, differentiation studies, and functional assays, providing a versatile platform for diverse experimental designs.
For researchers, the value of FAT4 Gene Knockout Cell Lines lies not only in their ability to aid in the understanding of fundamental biological questions but also in their potential to contribute to translational research aimed at novel therapies. By investing in this cutting-edge product, you align your work with the forefront of genetic research, powered by our commitment to high-quality biotechnological solutions and robust support for our users. Our expertise in developing precise genetic tools ensures that your research can progress with confidence in both quality and relevance.
Please note that all services are for research use only. Not intended for any clinical use.
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