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FAM83B Knockout Cell Lines

Gene: FAM83B

Official Full Name: family with sequence similarity 83 member Bprovided by HGNC

Gene Summary: Enables epidermal growth factor receptor binding activity; phosphatidylinositol 3-kinase binding activity; and protein kinase binding activity. Involved in cell population proliferation and positive regulation of epidermal growth factor receptor signaling pathway. Located in cytoplasm and membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27084 FAM83B Knockout cell line (HCT 116) Human FAM83B 1:2~1:4 Negative Online Inquiry
KO27085 FAM83B Knockout cell line (HEK293) Human FAM83B 1:3~1:6 Negative Online Inquiry

Background

FAM83B Gene Knockout Cell Lines are genetically engineered cell lines that specifically lack the FAM83B gene, a critical component implicated in various cellular processes including proliferation, differentiation, and signaling. By utilizing CRISPR-Cas9 technology, these cell lines allow for a precise alteration of the genomic sequence, thus eliminating the expression of FAM83B. This process enables researchers to study the gene’s function and its role in cellular mechanisms, particularly in the context of cancer biology, where FAM83B has been noted for its involvement in cancer progression and metastasis.

The primary function of FAM83B Gene Knockout Cell Lines is to facilitate the investigation of pathways regulated by FAM83B, providing insight into its contributions to oncogenic signaling and tumor development. By utilizing these knockout models, scientists can observe phenotypic changes and assess molecular alterations that occur in the absence of FAM83B expression. This enables in-depth studies into the gene’s role in cellular behavior, offering potential for the identification of novel therapeutic targets.

The scientific importance of FAM83B Gene Knockout Cell Lines extends to both fundamental research and clinical applications. Researchers investigating cancer mechanisms may benefit from understanding how the loss of FAM83B alters cell growth, migration, and response to treatments, thereby aiding in the development of targeted therapies. Clinicians exploring the prognostic implications of FAM83B expression levels in tumors can utilize these models to validate their findings, leading to improved patient stratification and outcomes.

Compared to existing alternatives, such as wild-type cell lines or transient knockdown models, FAM83B Gene Knockout Cell Lines provide a stable, long-term solution for studying gene function. The permanent knockout of FAM83B creates a consistent environment for research, eliminating variability associated with transient approaches and allowing for more reliable data interpretation.

For researchers, clinicians, and pharmaceutical developers seeking to understand the complexities of cancer biology and therapeutic interventions, FAM83B Gene Knockout Cell Lines represent a valuable tool. Their precise knockout capability and stability provide unmatched opportunities for discoveries that could lead to innovative cancer treatments. Our company, leveraging cutting-edge genomic engineering techniques and deep expertise in cellular biology, is committed to providing high-quality biological research products that empower scientific advancement.

Please note that all services are for research use only. Not intended for any clinical use.

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