Gene: ESRRB
Official Full Name: estrogen related receptor betaprovided by HGNC
Gene Summary: This gene encodes a protein with similarity to the estrogen receptor. Its function is unknown; however, a similar protein in mouse plays an essential role in placental development. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37949 | ESRRB Knockout cell line (HEK293) | Human | ESRRB | 1:3~1:6 | Negative | Online Inquiry |
ESRRB Gene Knockout Cell Lines are genetically engineered cellular models designed to study the effects of the estrogen-related receptor beta (ESRRB) gene by completely inhibiting its expression. Utilizing advanced CRISPR-Cas9 technology, these cell lines enable precise gene knockout, allowing researchers to dissect the physiological and cellular roles of ESRRB in various biological contexts, including embryonic stem cell differentiation, metabolism regulation, and hormone signaling pathways.
The primary mechanism of action involves the targeted cleavage of the ESRRB gene loci, resulting in frameshift mutations that effectively eliminate functional protein production. This creates a valuable platform for elucidating the contributions of ESRRB to critical biological processes. In research settings, these knockout cell lines serve as powerful tools for investigating gene function, validating drug targets, and exploring the molecular underpinnings of diseases such as cancer and metabolic disorders.
The scientific importance of ESRRB Gene Knockout Cell Lines cannot be overstated. Their applications extend beyond basic research; they are pivotal in preclinical studies that assess therapeutic interventions and the biological implications of estrogen signaling. This enables a more thorough understanding of tissue-specific mechanisms and responses to endocrine disruptors.
Compared to conventional manipulation techniques, ESRRB Gene Knockout Cell Lines offer higher specificity, efficiency, and reproducibility, minimizing off-target effects and providing a streamlined pathway to obtaining consistent results. Their well-characterized background ensures reliability in experimental replication, addressing a critical need in the research community for robust biological models.
For researchers and clinicians seeking to uncover the complexities of gene function and signaling networks, ESRRB Gene Knockout Cell Lines represent an indispensable resource. With our extensive expertise in genetic engineering and cell line development, we are committed to delivering high-quality biological products that empower scientific discovery and accelerate advancements in health-related research.
Please note that all services are for research use only. Not intended for any clinical use.
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