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EFCAB2 Knockout Cell Lines

Gene: EFCAB2

Official Full Name: dynein regulatory complex subunit 8provided by HGNC

Gene Summary: The gene encodes a protein that contains two EF-hand calcium-binding domains although its function has yet to be determined. Alternatively spliced transcripts have been observed. [provided by RefSeq, Mar 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24967 EFCAB2 Knockout cell line (HeLa) Human EFCAB2 1:3~1:6 Negative Online Inquiry
KO24968 EFCAB2 Knockout cell line (HCT 116) Human EFCAB2 1:2~1:4 Negative Online Inquiry
KO24969 EFCAB2 Knockout cell line (HEK293) Human EFCAB2 1:3~1:6 Negative Online Inquiry
KO24970 EFCAB2 Knockout cell line (A549) Human EFCAB2 1:3~1:4 Negative Online Inquiry

Background

EFCAB2 Gene Knockout Cell Lines are genetically modified cellular models designed to study the function of the EFCAB2 gene, a crucial player in various cellular processes, including calcium signaling and interactions with other proteins. By employing CRISPR-Cas9 genome editing technology, these cell lines provide a precise and efficient means to investigate gene function and the consequences of gene knockout on physiological and pathological conditions. The knockout mechanism involves targeted disruption of the EFCAB2 gene, which allows researchers to analyze gene-specific effects on cellular behavior, including proliferation, differentiation, and apoptotic pathways.

The scientific importance of EFCAB2 Gene Knockout Cell Lines lies in their ability to facilitate research in multiple areas, including cancer biology, neurobiology, and immunology. They serve as valuable tools for elucidating the gene's role in health and disease, allowing for the exploration of therapeutic targets and the development of novel interventions. Additionally, these cell lines can be utilized in drug screening assays, helping to identify compounds that may selectively modulate the pathways associated with EFCAB2 function.

Compared to other genetic manipulation techniques, these knockout cell lines offer several distinct advantages. They provide a stable genetic background, which ensures consistent and reproducible experimental results. Moreover, the specificity of CRISPR-Cas9 gene editing minimizes off-target effects, thereby improving the reliability of findings. Researchers will find the EFCAB2 knockout cell lines particularly beneficial for high-throughput screening, functional assays, and in-depth mechanistic studies.

The value of EFCAB2 Gene Knockout Cell Lines to researchers and clinicians is underscored by their potential to accelerate the understanding of complex biological processes and to inform the development of targeted therapies. By leveraging these powerful tools, scientists can gain deeper insights into gene functionality and its implications in disease states.

Our company, recognized for its commitment to advancing genetic research and providing high-quality biological products, stands at the forefront of genetic engineering innovation. We offer a comprehensive range of genetically modified cell lines that support cutting-edge research, ensuring that our customers have the necessary tools to make meaningful scientific discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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