Home / DLK2 Knockout Cell Lines

DLK2 Knockout Cell Lines

Gene: DLK2

Official Full Name: delta like non-canonical Notch ligand 2provided by HGNC

Gene Summary: Predicted to enable Notch binding activity. Involved in negative regulation of Notch signaling pathway. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18275 DLK2 Knockout cell line (HCT 116) Human DLK2 1:2~1:4 Negative Online Inquiry
KO18276 DLK2 Knockout cell line (HEK293) Human DLK2 1:3~1:6 Negative Online Inquiry
KO18277 DLK2 Knockout cell line (A549) Human DLK2 1:3~1:4 Negative Online Inquiry

Background

DLK2 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the expression of the DLK2 gene, which is implicated in various cellular processes, including neuronal differentiation and axon growth. By utilizing CRISPR-Cas9 technology for precise gene editing, these knockout cell lines provide a reliable tool for researchers studying the biological roles of DLK2 in cellular signaling pathways and its potential implications in neurodegenerative diseases and developmental disorders.

The primary function of the DLK2 Gene Knockout Cell Lines lies in their ability to facilitate in-depth studies of gene function and its associated signaling mechanisms. Without the expression of DLK2, researchers can observe downstream effects on neuronal growth and plasticity, allowing for a clearer understanding of the gene's role in developmental biology and disease progression. This functionality is essential for elucidating the molecular underpinnings of various neurological conditions, thereby opening avenues for targeted therapeutic strategies.

In terms of scientific importance, these knockout cell lines are invaluable in both research and clinical settings. They can be utilized to screen for potential pharmacological agents that may reverse or modify the effects of DLK2 deficiency, making them crucial in the field of neuropharmacology. They are also suitable for generating animal models with tailored genetic backgrounds, facilitating comprehensive in vivo studies.

The specific advantages of the DLK2 Gene Knockout Cell Lines over alternatives include their high specificity and efficiency, resulting from advanced gene editing techniques. Additionally, these lines are rigorously validated to ensure consistent performance, thus reducing variability in experimental outcomes. Their availability in a ready-to-use format allows researchers to expedite their studies without the need for extensive preliminary work or additional customization.

For researchers and clinicians, the value of our DLK2 Gene Knockout Cell Lines lies not only in their robust performance but also in their alignment with current trends in precision medicine and genetic research. Our expertise in custom cell line development ensures that these products meet the highest standards of quality and reliability, empowering the scientific community to further explore the complexities of genetic regulation and its implications for health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.