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DIRAS3 Knockout Cell Lines

Gene: DIRAS3

Official Full Name: DIRAS family GTPase 3provided by HGNC

Gene Summary: This gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex. [provided by RefSeq, Nov 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33599 DIRAS3 Knockout cell line (HeLa) Human DIRAS3 1:3~1:6 Negative Online Inquiry
KO33600 DIRAS3 Knockout cell line (HCT 116) Human DIRAS3 1:2~1:4 Negative Online Inquiry
KO33601 DIRAS3 Knockout cell line (A549) Human DIRAS3 1:3~1:4 Negative Online Inquiry

Background

DIRAS3 Gene Knockout Cell Lines represent a groundbreaking tool in molecular biology and genetics, specifically designed to study the implications of the DIRAS3 gene in various physiological and pathological processes. DIRAS3, a member of the Ras superfamily, plays a pivotal role in tumor suppression, cell signaling, and cellular differentiation. These knockout cell lines enable researchers to investigate the gene's functions by effectively disrupting its expression, thereby allowing for the assessment of its regulatory networks and interaction with other molecular pathways.

The primary function of these cell lines lies in their capability to provide a controlled environment for expression studies, facilitating the investigation of cellular responses following the loss of DIRAS3 function. Researchers can employ these models to examine the effects on cell proliferation, apoptosis, and metastasis, contributing to a deeper understanding of cancer biology and potential therapeutic targets. In addition, the DIRAS3 knockout cell lines can be invaluable for drug discovery processes, assisting in screening and characterizing compounds that might restore normal function or inhibit tumor growth.

In both research and clinical settings, the scientific importance of the DIRAS3 knockout cell lines is profound. They offer unique insights into the gene's role in human diseases, particularly in oncology, where understanding tumor suppressor mechanisms can lead to innovative treatment strategies. Their use can streamline the process of validating gene function in various cell types and provide a reliable basis for exploring gene therapy applications.

One of the distinct advantages of our DIRAS3 Gene Knockout Cell Lines is the rigor of their development, which includes robust quality control and validation processes, ensuring high reproducibility and reliability of results compared to alternative models, such as in vitro assays or less specific cellular systems.

Researchers, clinicians, and biotechnology firms seeking to enhance their investigative paradigms will find value in the precision that these cell lines offer to dissect complex gene functions and their implications. Our commitment to providing high-quality, innovative biological products is underscored by our expertise in molecular genetics. Trust in our offerings to empower your research and contribute to meaningful advancements in health and medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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