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DHRS4 Knockout Cell Lines

Gene: DHRS4

Official Full Name: dehydrogenase/reductase 4provided by HGNC

Gene Summary: Enables identical protein binding activity; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; and oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Involved in several processes, including ketone metabolic process; positive regulation of reactive oxygen species metabolic process; and steroid metabolic process. Located in nucleus and peroxisomal membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31432 DHRS4 Knockout cell line (HeLa) Human DHRS4 1:3~1:6 Negative Online Inquiry
KO31433 DHRS4 Knockout cell line (HCT 116) Human DHRS4 1:2~1:4 Negative Online Inquiry
KO31434 DHRS4 Knockout cell line (HEK293) Human DHRS4 1:3~1:6 Negative Online Inquiry
KO31435 DHRS4 Knockout cell line (A549) Human DHRS4 1:3~1:4 Negative Online Inquiry

Background

DHRS4 Gene Knockout Cell Lines represent a powerful tool in the realm of genetic and cellular research, designed specifically to investigate the biological functions of the DHRS4 gene and its implications in various metabolic pathways. These cell lines are engineered to lack the DHRS4 gene, enabling researchers to study the phenotypic and molecular changes that result from its absence, thereby elucidating the gene's role in cellular processes such as steroidogenesis and lipid metabolism.

The key functions of these knockout cell lines lie in their ability to facilitate the analysis of metabolic alterations that occur in the absence of DHRS4 expression. By utilizing techniques such as transcriptomics, proteomics, and metabolic profiling on these cells, researchers can map out the downstream effects on signaling pathways and evaluate potential compensatory mechanisms or alternative pathways that might be activated in response to the gene knockout. This mechanistic understanding is crucial in fields ranging from pharmacology to developmental biology, where DHRS4's involvement in disease states like metabolic syndrome, obesity, and cancer is under investigation.

The scientific importance of DHRS4 Gene Knockout Cell Lines is profound, as they provide a model to uncover novel therapeutic targets and enhance the understanding of diseases associated with aberrant DHRS4 function. Clinically, insights gained from using these models may lead to the development of innovative treatment strategies aimed at metabolic disorders.

What sets our DHRS4 Gene Knockout Cell Lines apart from alternatives is their high specificity and reproducibility, ensuring that researchers achieve consistent and reliable results. Furthermore, they are developed using the latest CRISPR/Cas9 gene-editing technology, lowering off-target effects while maximizing efficiency. This makes them a superior choice for researchers keen on maintaining the integrity of their experimental conditions while pursuing cutting-edge findings.

In summary, the DHRS4 Gene Knockout Cell Lines present a valuable asset for both researchers and clinicians, offering deep insights into gene function and potential therapeutic avenues. At [Company Name], our expertise in genetic engineering and commitment to quality ensure that our products meet rigorous scientific standards, empowering users to advance their research and clinical objectives effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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