Gene: DDX31
Official Full Name: DEAD-box helicase 31provided by HGNC
Gene Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18355 | DDX31 Knockout cell line (HeLa) | Human | DDX31 | 1:3~1:6 | Negative | Online Inquiry |
KO18356 | DDX31 Knockout cell line (HCT 116) | Human | DDX31 | 1:2~1:4 | Negative | Online Inquiry |
KO18357 | DDX31 Knockout cell line (HEK293) | Human | DDX31 | 1:3~1:6 | Negative | Online Inquiry |
KO18358 | DDX31 Knockout cell line (A549) | Human | DDX31 | 1:3~1:4 | Negative | Online Inquiry |
DDX31 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to have the DDX31 gene silenced or inactivated. The DDX31 gene encodes a DEAD-box helicase, which plays a crucial role in various cellular processes including RNA metabolism, ribosome biogenesis, and response to cellular stress. By utilizing CRISPR/Cas9 technology, these knockout cell lines allow researchers to investigate the functional significance of DDX31 in cellular pathways and disease mechanisms, providing a valuable model for studying conditions such as cancer and developmental disorders.
The key function of DDX31 knockout is to elucidate the downstream effects of the absence of this helicase on cellular processes. Specifically, these cell lines facilitate the analysis of changes in gene expression, protein synthesis, and overall cell viability. Researchers can examine the impact of DDX31 deficiency on cellular responses to environmental stress, apoptosis, and proliferation, thus enhancing understanding of its role in pathophysiology.
The scientific importance of these knockout cell lines extends to both basic and applied research settings. They are invaluable tools for functional genomics, drug discovery, and therapeutic development, as they enable a more profound understanding of DDX31's role in various diseases. Furthermore, they can be instrumental in screening compounds that target DDX31-associated pathways, providing insights into potential therapeutic interventions.
What sets DDX31 Gene Knockout Cell Lines apart from other knockout models is their precision and the breadth of applications they support. While many alternative products may not offer the same level of specificity, our DDX31 knockout lines exhibit consistent performance across various experimental platforms, ensuring reproducibility and reliability in research outcomes. Their optimized culture conditions and validation against multiple genetic backgrounds make them an attractive choice for researchers looking to explore this gene's functional landscape.
By choosing DDX31 Gene Knockout Cell Lines, researchers and clinicians gain access to a powerful tool that enhances their investigative capabilities and accelerates the pursuit of biological knowledge. Our company prides itself on delivering high-quality, rigorously validated biological products, underscoring our commitment to advancing scientific exploration and therapeutic innovation.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.