Gene: DAPK2
Official Full Name: death associated protein kinase 2provided by HGNC
Gene Summary: This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29077 | DAPK2 Knockout cell line (HeLa) | Human | DAPK2 | 1:3~1:6 | Negative | Online Inquiry |
KO29078 | DAPK2 Knockout cell line (HCT 116) | Human | DAPK2 | 1:2~1:4 | Negative | Online Inquiry |
KO29079 | DAPK2 Knockout cell line (A549) | Human | DAPK2 | 1:3~1:4 | Negative | Online Inquiry |
DAPK2 Gene Knockout Cell Lines are advanced model systems designed for the precise study of the DAPK2 (Death-Associated Protein Kinase 2) gene, a critical component involved in various cellular processes, including apoptosis, autophagy, and inflammation. These cell lines are engineered through CRISPR/Cas9 technology, allowing for the knockout of the DAPK2 gene, thereby providing researchers with insights into its functional roles within different biological contexts.
The key mechanism of DAPK2 Gene Knockout Cell Lines lies in their ability to facilitate the examination of cellular signaling pathways and stress responses without the influence of DAPK2-mediated activities. Researchers can utilize these cell lines to dissect the role of DAPK2 in cancer progression, neurological disorders, and immune responses, effectively contributing to the understanding of its involvement in pathophysiological conditions. This model is invaluable for preclinical studies and therapeutic development, particularly as it helps elucidate potential targets for novel drug interventions.
Scientific studies leveraging DAPK2 knockouts have proven critical in expanding the understanding of mechanisms related to cell death and survival, making these cell lines exceptionally relevant in both research and clinical settings. Unlike traditional approaches that may involve pharmacological inhibition of protein function, our DAPK2 gene knockout cell lines offer a more specific, permanent solution that eliminates ambiguity in experimental results.
With superior specificity and reproducibility, our cell lines empower researchers and clinicians by providing robust tools that streamline experimental workflows and advance the translation of findings from bench to bedside. These unique attributes facilitate the study of DAPK2 in an unconfounded manner, enabling the identification of novel biomarkers and therapeutic strategies in complex diseases.
As a leader in biological product development, our company is committed to providing high-quality, innovative tools that drive scientific discovery. With a focus on precision and reliability, we are dedicated to supporting the ongoing research efforts directed at unraveling the intricacies of cellular processes through targeted genetic manipulation.
Please note that all services are for research use only. Not intended for any clinical use.
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