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DACT3 Knockout Cell Lines

Gene: DACT3

Official Full Name: dishevelled binding antagonist of beta catenin 3provided by HGNC

Gene Summary: Predicted to enable delta-catenin binding activity; protein kinase A binding activity; and protein kinase C binding activity. Involved in negative regulation of canonical Wnt signaling pathway and negative regulation of cell growth. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23582 DACT3 Knockout cell line (HCT 116) Human DACT3 1:2~1:4 Negative Online Inquiry
KO23583 DACT3 Knockout cell line (HEK293) Human DACT3 1:3~1:6 Negative Online Inquiry

Background

DACT3 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the study of the DACT3 gene’s role in various biological processes. These cell lines are created through a targeted gene editing technique—typically CRISPR-Cas9—resulting in precise deletions of the DACT3 gene. By completely knocking out this gene, researchers can effectively disrupt its function and observe the resultant phenotypic changes, aiding in the understanding of cellular pathways and disease mechanisms associated with DACT3.

The primary function of the DACT3 gene pertains to its involvement in the Wnt signaling pathway, which plays a critical role in cell proliferation, differentiation, and embryonic development. By utilizing DACT3 Gene Knockout Cell Lines, researchers can unravel the complex interactions within this pathway, exploring how disruptions contribute to oncogenesis, regenerative medicine, and other pathologies. The ability to analyze gene function in these models is invaluable for drug discovery and basic research, enabling scientists to evaluate potential therapeutic targets.

One of the unique advantages of using DACT3 Gene Knockout Cell Lines lies in their specificity and reproducibility compared to traditional methods, such as chemical inhibitors or non-specific RNA interference, which may have off-target effects. Additionally, these cell lines provide a stable expression environment, allowing for the consistent study of gene function across experiments.

Investing in DACT3 Gene Knockout Cell Lines empowers researchers and clinicians to gain deeper insights into the gene's physiological roles and its implications in various diseases. This functional understanding is particularly crucial in the development of novel therapeutic strategies targeting aberrant Wnt signaling linked to cancer.

With a commitment to advancing genetic and cellular technologies, our company offers a robust pipeline of gene knockout models, including DACT3, underpinned by years of expertise in molecular biology and cell engineering. Our products are designed to support groundbreaking research and to drive innovations in the field of biomedical science.

Please note that all services are for research use only. Not intended for any clinical use.

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