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DACH1 Knockout Cell Lines

Gene: DACH1

Official Full Name: dachshund family transcription factor 1provided by HGNC

Gene Summary: This gene encodes a chromatin-associated protein that associates with other DNA-binding transcription factors to regulate gene expression and cell fate determination during development. The protein contains a Ski domain that is highly conserved from Drosophila to human. Expression of this gene is lost in some forms of metastatic cancer, and is correlated with poor prognosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38304 DACH1 Knockout cell line (HEK293) Human DACH1 1:3~1:6 Negative Online Inquiry

Background

DACH1 Gene Knockout Cell Lines are specialized cell lines engineered to lack the expression of the DACH1 gene, a critical regulator of various cellular processes, including development, differentiation, and signaling pathways. By employing CRISPR-Cas9 technology, these cell lines provide a powerful tool for elucidating the functional roles of DACH1 in a variety of biological contexts.

The primary function of DACH1 is to modulate gene expression related to developmental pathways and is implicated in cancer progression. By knocking out the DACH1 gene, researchers can investigate the downstream effects on cellular behavior, morphology, and signaling mechanisms. This offers insights into how the absence of DACH1 influences processes such as cell cycle regulation and apoptosis, thereby advancing our understanding of its role in both normal physiology and disease.

The scientific significance of DACH1 Gene Knockout Cell Lines extends to multiple research avenues, including cancer biology, developmental biology, and therapeutic development. Clinically, these cell lines can be utilized to explore potential therapeutic targets for diseases characterized by aberrant DACH1 expression, such as various cancers. With the ongoing interest in targeted therapies, understanding DACH1’s function is becoming increasingly crucial.

What sets DACH1 Gene Knockout Cell Lines apart from alternatives is their precision and reliability; engineered using state-of-the-art gene-editing techniques, they ensure a consistent phenotype essential for reproducible results. Additionally, these cell lines come with detailed characterization data, enabling researchers to readily confirm the loss-of-function of DACH1.

For researchers and clinicians, DACH1 Gene Knockout Cell Lines represent a valuable asset that facilitates groundbreaking research leading to novel therapeutic interventions. Our expertise in gene editing and cell line development guarantees that users will receive high-quality products tailored to meet their specific research needs. As a leader in biological products, we are committed to providing innovative tools that drive scientific discovery forward.

Please note that all services are for research use only. Not intended for any clinical use.

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