Gene: DAB1
Official Full Name: DAB adaptor protein 1provided by HGNC
Gene Summary: The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. [provided by RefSeq, Jan 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO38309 | DAB1 Knockout cell line (HeLa) | Human | DAB1 | 1:3~1:6 | Negative | Online Inquiry |
DAB1 Gene Knockout Cell Lines represent a groundbreaking innovation in the field of molecular biology, specifically targeting the DAB1 gene, which is integral to neuronal signaling and development. These specifically designed cell lines are generated using CRISPR/Cas9 technology to facilitate the complete knockout of the DAB1 gene, providing researchers with vital tools to explore the gene’s role in cellular processes and its implications in neurological disorders.
The primary function of these knockout cell lines is to enable in-depth studies of the signaling pathways influenced by the DAB1 gene. By investigating the resultant phenotypic changes in neuronal and non-neuronal contexts, researchers can gain insights into the molecular mechanisms of diseases such as schizophrenia and autism spectrum disorders, which have been associated with aberrations in DAB1 signaling. This product thus provides a unique platform for functional studies, drug screening, and the evaluation of therapeutic approaches targeting DAB1-related pathways.
In scientific research and clinical applications, the importance of DAB1 Gene Knockout Cell Lines cannot be overstated. They serve as essential models for investigating gene function, gene interactions, and the broader implications of genetic variations on neuronal development and health. Compared to traditional models, these knockout lines offer higher specificity and reproducibility, making them invaluable for researchers looking to apply precise genetic manipulation techniques.
What sets DAB1 Gene Knockout Cell Lines apart from alternatives is their unparalleled specificity and the advanced, high-efficiency CRISPR/Cas9 gene editing technique employed in their creation. This not only minimizes off-target effects but also enhances the reproducibility of experimental outcomes. The user-friendly nature of these cell lines expedites research timelines, allowing scientists to focus on results rather than troubleshooting common pitfalls associated with alternative models.
Investing in DAB1 Gene Knockout Cell Lines is a paramount choice for researchers and clinicians who are seeking reliable, efficient, and scientifically vetted resources to deepen their understanding of gene function and its implications in health and disease. Our company brings expertise in genetic engineering and molecular biology, ensuring that our product offerings meet the highest standards of quality and reliability, empowering researchers in their quest for scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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