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CYP8B1 Knockout Cell Lines

Gene: CYP8B1

Official Full Name: cytochrome P450 family 8 subfamily B member 1provided by HGNC

Gene Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the cytochrome P450 genes in that it is intronless. [provided by RefSeq, Jul 2008]

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Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KOA16298 CYP8B1 Knockout cell line (AC16) Human CYP8B1 1:3-1:4 negative Online Inquiry
KOA31745 CYP8B1 Knockout cell line (BEAS-2B) Human CYP8B1 1:3~1:4 negative Online Inquiry
KOA47162 CYP8B1 Knockout cell line (U-2932) Human CYP8B1 1:2-1:4 negative Online Inquiry
KOA62559 CYP8B1 Knockout cell line (TPC-1) Human CYP8B1 1:5-1:8 negative Online Inquiry
KOA77984 CYP8B1 Knockout cell line (NCM460) Human CYP8B1 1:2~1:3 negative Online Inquiry

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