Gene: CYP2S1
Official Full Name: cytochrome P450 family 2 subfamily S member 1provided by HGNC
Gene Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04609 | CYP2S1 Knockout cell line (HeLa) | Human | CYP2S1 | 1:3~1:6 | Negative | Online Inquiry |
KO04610 | CYP2S1 Knockout cell line (HCT 116) | Human | CYP2S1 | 1:2~1:4 | Negative | Online Inquiry |
KO04611 | CYP2S1 Knockout cell line (A549) | Human | CYP2S1 | 1:3~1:4 | Negative | Online Inquiry |
CYP2S1 Gene Knockout Cell Lines are uniquely engineered cellular models that feature a targeted disruption of the CYP2S1 gene, which encodes for the enzyme cytochrome P450 2S1. This gene plays a critical role in the metabolism of various endogenous and exogenous compounds, including important signaling molecules and drugs. By knocking out CYP2S1, these cell lines provide invaluable insights into the physiological and pathological roles of this enzyme in drug metabolism, toxicology, and disease processes.
The primary function of these knockout cell lines lies in their ability to facilitate the study of CYP2S1-related pathways and cellular responses without the confounding effects of the enzyme's activity. Researchers can utilize these models to assess changes in drug pharmacokinetics, evaluate the impact of metabolic alterations on cellular functions, and investigate the implications of CYP2S1 interactions with other biochemical pathways. Moreover, these cell lines can serve as platforms for drug discovery and development, enabling the identification of potential therapeutic targets for diseases influenced by cytochrome P450 enzymes.
In both research and clinical settings, CYP2S1 Gene Knockout Cell Lines are critical for advancing our understanding of cytochrome P450 biology and its clinical relevance. Their utility in elucidating mechanisms of drug resistance, toxicology studies, and personalized medicine applications adds notable scientific importance.
What distinguishes these knockout cell lines from alternatives is their precise gene editing and validation, ensuring reliable and reproducible results. Unlike other non-specific approaches, the targeted knockout technique fosters higher specificity in research findings, enhancing experimental accuracy.
By integrating CYP2S1 Gene Knockout Cell Lines into your research, you empower your investigations with cutting-edge tools that can accelerate discovery and innovation. Our company embodies expertise in providing high-quality biological models, ensuring that customers have access to exceptional products designed to meet the rigorous demands of modern scientific inquiry.
Please note that all services are for research use only. Not intended for any clinical use.
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