Gene: CTNNA3
Official Full Name: catenin alpha 3provided by HGNC
Gene Summary: This gene encodes a protein that belongs to the vinculin/alpha-catenin family. The encoded protein plays a role in cell-cell adhesion in muscle cells. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia, familial 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO08482 | CTNNA3 Knockout cell line (HEK293) | Human | CTNNA3 | 1:3~1:6 | Negative | Online Inquiry |
CTNNA3 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the CTNNA3 gene, which encodes the alpha-catenin-3 protein. This gene plays an integral role in cellular adhesion, cytoskeletal organization, and signaling pathways. By utilizing CRISPR-Cas9 or other gene-editing technologies, our knockout cell lines provide researchers with invaluable tools for investigating the functional consequences of CTNNA3 deficiency.
These cell lines facilitate the exploration of key cellular processes such as epithelial-to-mesenchymal transition (EMT), cell proliferation, and apoptosis, providing insights into oncogenesis and cancer progression. The absence of CTNNA3 allows for the dissection of its role in various cellular contexts, enabling researchers to elucidate the gene's involvement in diseases like cancer and developmental disorders. Therefore, these models hold significant scientific importance, serving not just as experimental platforms but as integral components of translational research aimed at identifying novel therapeutic targets.
What sets our CTNNA3 Gene Knockout Cell Lines apart from alternatives is the rigor of our validation processes. Each cell line is thoroughly characterized for gene knockout efficiency, stability over time, and functional assays to ensure consistency and reliability in experimental outcomes. Furthermore, our cell lines are derived from commonly studied human tissues, which enhances their relevance for translational research.
For researchers and clinicians looking to expand their understanding of gene function in human diseases, our CTNNA3 Gene Knockout Cell Lines offer an unparalleled opportunity to streamline research efforts and achieve robust findings. With a commitment to quality and reliability, our company is dedicated to providing innovative biological products that empower scientific discovery and clinical advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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