Gene: CRYZL1
Official Full Name: crystallin zeta like 1provided by HGNC
Gene Summary: This gene encodes a protein that has sequence similarity to zeta crystallin, also known as quinone oxidoreductase. This zeta crystallin-like protein also contains an NAD(P)H binding site. Alternatively spliced transcript variants have been observed but their full-length nature has not been completely determined. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32457 | CRYZL1 Knockout cell line (HeLa) | Human | CRYZL1 | 1:3~1:6 | Negative | Online Inquiry |
KO32458 | CRYZL1 Knockout cell line (HCT 116) | Human | CRYZL1 | 1:2~1:4 | Negative | Online Inquiry |
KO32459 | CRYZL1 Knockout cell line (HEK293) | Human | CRYZL1 | 1:3~1:6 | Negative | Online Inquiry |
KO32460 | CRYZL1 Knockout cell line (A549) | Human | CRYZL1 | 1:3~1:4 | Negative | Online Inquiry |
CRYZL1 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to analyze the role of the CRYZL1 gene in various biological processes. These cell lines have undergone precise knockout techniques that inhibit the expression of the CRYZL1 gene, allowing researchers to investigate the gene's function and its implications in health and disease. The CRYZL1 protein, a member of the scavenger receptor family, plays a significant role in cellular metabolism and immune response, making it a crucial target for studying pathophysiological conditions.
The key mechanism behind the knockout cell lines involves the use of CRISPR/Cas9 technology, which allows for highly specific alterations in the genome. By inducing double-strand breaks at the CRYZL1 locus, researchers can create frameshift mutations leading to a loss of function. This allows for a wide range of investigation into the molecular pathways affected by the absence of CRYZL1, including those related to cellular stress responses and potential implications in oncogenesis.
The scientific importance of CRYZL1 Gene Knockout Cell Lines extends to both fundamental research and clinical applications. They provide an invaluable tool for drug discovery by allowing scientists to conduct functional assays that assess therapeutic interventions targeting CRYZL1-associated pathways. Additionally, these models are instrumental in elucidating the gene's role in various diseases, including autoimmune disorders and cancers, thus contributing to the development of targeted therapies.
Distinct advantages of CRYZL1 Gene Knockout Cell Lines include their reliability, reproducibility, and high specificity compared to traditional knockdown approaches, such as RNA interference. This results in more consistent experimental outcomes, reducing variability and enhancing the robustness of research findings.
Researchers and clinicians will find great value in utilizing CRYZL1 Gene Knockout Cell Lines as they represent a cutting-edge advancement in genetic engineering, enabling deeper insights into gene function and its broader implications in biology and medicine. With our commitment to excellence and ongoing innovations in biological research tools, our company is dedicated to providing high-quality cellular models that empower the scientific community to make significant advancements in health and disease understanding.
Please note that all services are for research use only. Not intended for any clinical use.
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