Gene: COL23A1
Official Full Name: collagen type XXIII alpha 1 chainprovided by HGNC
Gene Summary: COL23A1 is a member of the transmembrane collagens, a subfamily of the nonfibrillar collagens that contain a single pass hydrophobic transmembrane domain (Banyard et al., 2003 [PubMed 12644459]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23453 | COL23A1 Knockout cell line (HEK293) | Human | COL23A1 | 1:3~1:6 | Negative | Online Inquiry |
COL23A1 Gene Knockout Cell Lines are highly specialized research tools developed for the study of the collagen type XXIII alpha 1 (COL23A1) gene, which is implicated in various biological processes including tissue remodeling and cell signaling pathways. These cell lines are genetically engineered to have a complete knockout of the COL23A1 gene, allowing researchers to investigate its function in cellular contexts and elucidate its role in health and disease.
The primary mechanism by which these cell lines operate is through the elimination of COL23A1 expression, providing a unique model to study the downstream biological effects of this gene's absence. This functional loss is crucial for dissecting the molecular pathways in which COL23A1 might be involved and can affect processes such as cell adhesion, migration, and proliferation. By utilizing these cell lines, researchers can gain invaluable insights into conditions such as cancer, fibrosis, and other collagen-related disorders.
Scientifically, these cell lines hold significant importance for both fundamental and applied research. In clinical settings, understanding the role of COL23A1 could lead to novel therapeutic strategies or biomarkers for disease progression. Moreover, these models facilitate high-throughput screening of drug candidates targeting the pathways influenced by COL23A1, making them vital for translational research.
Compared to traditional wild-type cell lines, the COL23A1 Gene Knockout Cell Lines present unique advantages. Their precise genetic modification allows for more accurate modeling of biological processes associated with COL23A1 absence, minimizing confounding variables often present in non-targeted cell lines. This specificity enhances experimental reproducibility and reliability, thereby increasing the overall quality of research outcomes.
For researchers and clinicians delving into collagen-associated diseases or regenerative medicine, COL23A1 Gene Knockout Cell Lines are invaluable. They not only streamline the research process but also facilitate the generation of impactful results that can pave the way towards innovative clinical applications.
Our company specializes in the production of high-quality cellular models and genetic tools, leveraging cutting-edge technologies to enable breakthroughs in medical research. With our expertise in gene editing and cell line development, we provide products that are designed to meet the specific needs of researchers aiming to push the boundaries of scientific knowledge and therapeutic innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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