Gene: CNKSR2
Official Full Name: connector enhancer of kinase suppressor of Ras 2provided by HGNC
Gene Summary: This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30247 | CNKSR2 Knockout cell line (A549) | Human | CNKSR2 | 1:3~1:4 | Negative | Online Inquiry |
CNKSR2 Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the study of the CNKSR2 gene’s functions by completely disrupting its expression. These knockout cell lines create an invaluable resource for researchers investigating the role of CNKSR2 in various biological processes, including cellular signaling pathways, protein-protein interactions, and developmental biology.
The primary mechanism by which these cell lines operate is through the introduction of targeted genetic modifications via CRISPR-Cas9 or other gene-editing technologies. By creating precise deletions in the CNKSR2 gene, researchers can investigate the resultant phenotypic changes in cellular behavior, enabling a deeper understanding of the gene's involvement in health and disease. This characteristic makes the CNKSR2 knockout cell lines particularly advantageous for elucidating mechanisms underlying various conditions, such as neurodevelopmental disorders and cancer.
In terms of scientific importance, these cell lines are instrumental for both fundamental research and translational applications. They serve as a critical tool for drug discovery and development, providing insights into potential therapeutic targets related to diseases linked to aberrant signaling pathways catalyzed by CNKSR2. The ability to model disease states accurately with these knockout cells empowers researchers to explore novel therapeutic strategies and identify biomarkers for clinical research.
What sets CNKSR2 Gene Knockout Cell Lines apart from alternative models is their high specificity and reproducibility. Unlike traditional knockout models that may have variable genetic backgrounds, these cell lines are rigorously validated and standardize a pathway for consistent results, facilitating more reliable experimental outcomes. Their ease of use in various assays, including functional studies and high-throughput screening, further enhances their appeal.
In summary, CNKSR2 Gene Knockout Cell Lines are a pivotal resource for investigators aiming to advance our knowledge of genetic contributions to disease. Their impactful applications reinforce their value to researchers and clinicians alike. Backed by our company’s extensive expertise in genetic engineering and cell line development, we are committed to providing high-quality biological products tailored to meet the needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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