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CLSTN3 Knockout Cell Lines

Gene: CLSTN3

Official Full Name: calsyntenin 3provided by HGNC

Gene Summary: Enables cell-cell adhesion mediator activity and neurexin family protein binding activity. Involved in L-ascorbic acid metabolic process and regulation of synapse assembly. Predicted to be located in several cellular components, including Golgi membrane; dendrite; and postsynaptic density. Predicted to be part of protein-containing complex. Predicted to be active in several cellular components, including GABA-ergic synapse; lipid droplet; and postsynaptic density membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32828 CLSTN3 Knockout cell line (HeLa) Human CLSTN3 1:3~1:6 Negative Online Inquiry
KO32829 CLSTN3 Knockout cell line (HCT 116) Human CLSTN3 1:2~1:4 Negative Online Inquiry
KO32830 CLSTN3 Knockout cell line (HEK293) Human CLSTN3 1:3~1:6 Negative Online Inquiry
KO32831 CLSTN3 Knockout cell line (A549) Human CLSTN3 1:3~1:4 Negative Online Inquiry

Background

CLSTN3 Gene Knockout Cell Lines are specifically engineered cellular models where the CLSTN3 gene has been selectively disrupted or knocked out, leading to the study of its biological role and implications in various physiological processes. This type of cell line serves as a crucial tool for understanding gene function and the pathophysiology of conditions associated with CLSTN3, which has been linked to neuronal development and various neurodevelopmental disorders.

The primary function of these knockout cell lines centers around elucidating the role of CLSTN3 in cell signaling pathways and synaptic functions, often utilizing CRISPR-Cas9 or other genome editing techniques for precise gene disruption. By studying these cell lines, researchers can investigate alterations in cellular behavior, including proliferation, differentiation, and response to external stimuli, providing insights into neurological conditions attributable to CLSTN3 dysregulation.

The scientific importance of CLSTN3 Gene Knockout Cell Lines extends to applications in both research and clinical settings, particularly in the fields of neuroscience and genetics. They facilitate the identification of potential therapeutic targets and biomarker development, contributing to a broader understanding of diseases like autism spectrum disorders and schizophrenia that are influenced by synaptic dysfunction.

One of the standout advantages of using our CLSTN3 knockout cell lines is the high specificity and reproducibility of results compared to conventional models, such as induced pluripotent stem cells (iPSCs) or transgenic mice. These cell lines offer a cost-effective, scalable option for high-throughput screening and functional assays, allowing for quicker experimental turnaround.

For researchers and clinicians seeking to unravel the complexities of neurodevelopmental disorders, our CLSTN3 Gene Knockout Cell Lines represent an invaluable resource. They not only streamline experimental workflows but also enhance the potential for discovering novel therapeutic strategies.

In offering these advanced genetic tools, our company stands at the forefront of biotechnological innovation, dedicated to supporting the scientific community with high-quality product offerings that drive impactful research.

Please note that all services are for research use only. Not intended for any clinical use.

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