CLDN18 Knockout Cell Lines

Gene: CLDN18

Official Full Name: claudin 18provided by HGNC

Gene Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010]

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Products

Catalog Number	Product Name	Species	Gene	Passage ratio	Mycoplasma testing	Price
KOA09545	CLDN18 Knockout cell line (AC16)	Human	CLDN18	1：3-1：4	negative	Online Inquiry
KOA24992	CLDN18 Knockout cell line (BEAS-2B)	Human	CLDN18	1:3~1:4	negative	Online Inquiry
KOA40438	CLDN18 Knockout cell line (U-2932)	Human	CLDN18	1：2-1：4	negative	Online Inquiry
KOA55826	CLDN18 Knockout cell line (TPC-1)	Human	CLDN18	1:5-1:8	negative	Online Inquiry
KOA71244	CLDN18 Knockout cell line (NCM460)	Human	CLDN18	1:2~1:3	negative	Online Inquiry

Please note that all services are for research use only. Not intended for any clinical use.

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