Gene: CFAP54
Official Full Name: cilia and flagella associated protein 54provided by HGNC
Gene Summary: Predicted to be involved in cilium assembly; cilium movement involved in cell motility; and spermatogenesis. Predicted to act upstream of or within epithelial cilium movement involved in extracellular fluid movement; establishment of localization in cell; and sperm flagellum assembly. Predicted to be located in axoneme. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24098 | CFAP54 Knockout cell line (HEK293) | Human | CFAP54 | 1:3~1:6 | Negative | Online Inquiry |
CFAP54 Gene Knockout Cell Lines are a specialized biological tool designed for the study of CFAP54 gene function and its related pathways. These cell lines have been genetically engineered to eliminate the CFAP54 gene, providing a valuable platform for researchers to explore the consequences of CFAP54 loss on cellular processes, phenotype expression, and molecular interactions.
The primary function of CFAP54 gene knockout cell lines lies in their ability to facilitate the exploration of CFAP54's role in motility, cell signaling, and reproductive biology, particularly in the context of cilia function and sperm motility. The use of CRISPR-Cas9 gene editing techniques ensures precise and efficient knockout, allowing for the study of phenotypic changes associated with gene loss. This includes examining alterations in cellular morphology, motility assay performance, and related gene expression profiles.
Scientifically, these cell lines are significant in both basic and translational research settings. They enable scientists to unravel complex biological mechanisms related to ciliopathies and male infertility, as well as their potential implications in developmental biology and genomics. In clinical settings, understanding the functional outcomes associated with CFAP54 knockout could lead to novel biomarkers and targetable therapeutic strategies for related disorders.
CFAP54 Gene Knockout Cell Lines offer distinct advantages over traditional methods, such as transient gene silencing or overexpression studies, by providing a stable and reproducible model with a definitive genetic makeup. This specificity enhances the reliability of experimental results, making them more applicable to in vivo studies.
For researchers and clinicians, utilizing CFAP54 Gene Knockout Cell Lines means gaining access to robust, validated tools essential for advancing our understanding of critical biological pathways. Their unique characteristics streamline experimental workflows and enhance the depth of insights achievable within research projects.
With a commitment to cutting-edge biological innovations, our company specializes in the development of precise genetic models and cellular systems, ensuring that researchers have the most effective resources at their disposal for groundbreaking studies in genetics and cell biology.
Please note that all services are for research use only. Not intended for any clinical use.
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