Gene: CDK10
Official Full Name: cyclin dependent kinase 10provided by HGNC
Gene Summary: The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01783 | CDK10 Knockout cell line (HeLa) | Human | CDK10 | 1:3~1:6 | Negative | Online Inquiry |
KO01784 | CDK10 Knockout cell line (HCT 116) | Human | CDK10 | 1:2~1:4 | Negative | Online Inquiry |
KO01785 | CDK10 Knockout cell line (HEK293) | Human | CDK10 | 1:3~1:6 | Negative | Online Inquiry |
KO01786 | CDK10 Knockout cell line (A549) | Human | CDK10 | 1:3~1:4 | Negative | Online Inquiry |
CDK10 Gene Knockout Cell Lines represent a cutting-edge advancement in genetic research, specifically designed to investigate the functional roles of the cyclin-dependent kinase 10 (CDK10) gene. By employing CRISPR-Cas9 gene editing technologies, these cell lines have been meticulously developed to ablate the expression of CDK10, allowing scientists to explore the biochemical and molecular pathways modulated by this important regulator of the cell cycle.
The mechanism underlying these knockout cell lines hinges on the specific inactivation of the CDK10 gene, which encodes a protein kinase crucial for normal cell cycle progression and gene transcription regulation. In the absence of CDK10, researchers can examine cellular responses, alterations in signaling pathways, and perturbations in cellular proliferation, providing insights into CDK10's role in cancer biology and potential therapeutic targets.
The scientific importance of CDK10 Knockout Cell Lines extends to various research fields, including cancer research, developmental biology, and personalized medicine. Their ability to serve as a reliable model system enables researchers to study the implications of CDK10 dysregulation in disease processes, paving the way for novel therapeutic strategies and biomarker identification.
What sets these cell lines apart from alternatives is their high specificity, reproducibility, and the comprehensive validation of knockout efficiency. This ensures that experimental outcomes are attributable solely to CDK10 loss, minimizing off-target effects commonly associated with other genetic manipulation techniques. Furthermore, the user-friendly protocols provided by our team streamline the integration into laboratory workflows, enhancing productivity.
For researchers and clinicians alike, the ability to elucidate the biological significance of CDK10 will foster innovations in targeted therapies, particularly in oncology, where CDK10's functions may influence drug sensitivity and resistance. Our commitment to quality and rigorous scientific validation ensures that you will receive a product that meets your experimental needs, backed by our extensive expertise in biological product development and gene editing technologies.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.