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CCHCR1 Knockout Cell Lines

Gene: CCHCR1

Official Full Name: coiled-coil alpha-helical rod protein 1provided by HGNC

Gene Summary: This gene encodes a protein with five coiled-coil alpha-helical rod domains that is thought to act as a regulator of mRNA metabolism through its interaction with mRNA-decapping protein 4. It localizes to P-bodies, the site of mRNA metabolism, with an N-terminus that is required for this subcellular localization, suggesting it is a P-body component. Naturally occurring mutations in this gene are associated with psoriasis. [provided by RefSeq, May 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01019 CCHCR1 Knockout cell line (HEK293) Human CCHCR1 1:3~1:6 Negative Online Inquiry
KO01478 CCHCR1 Knockout cell line(KYSE-30) Human CCHCR1 1:2~1:4 Negative Online Inquiry
KO18921 CCHCR1 Knockout cell line (HeLa) Human CCHCR1 1:3~1:6 Negative Online Inquiry
KO18922 CCHCR1 Knockout cell line (HCT 116) Human CCHCR1 1:2~1:4 Negative Online Inquiry
KO18923 CCHCR1 Knockout cell line (A549) Human CCHCR1 1:3~1:4 Negative Online Inquiry

Background

CCHCR1 Gene Knockout Cell Lines consist of genetically modified cell lines in which the CCHCR1 (Chemokine (C-C motif) receptor 1) gene has been precisely disrupted using advanced CRISPR-Cas9 technology. This gene is implicated in various immune responses and has been associated with susceptibility to autoimmune diseases. The knockout of CCHCR1 allows researchers to elucidate the role of this gene in cellular mechanisms and inflammation pathways, facilitating a deeper understanding of its contribution to health and disease.

These cell lines function by providing a robust model system for investigating the biological effects of CCHCR1 deletion on cell signaling, immune cell migration, and cytokine production. By studying these alterations, scientists can gain insights into the pathogenesis of autoimmune conditions and explore potential therapeutic targets that can mitigate inflammatory responses.

The scientific significance of CCHCR1 Gene Knockout Cell Lines extends to various research and clinical applications, including drug discovery, biomarker identification, and the development of novel therapeutic interventions. By effectively mimicking conditions associated with CCHCR1 dysregulation, these cell lines serve as valuable tools for pharmacological testing and personalized medicine approaches.

What sets CCHCR1 Gene Knockout Cell Lines apart from existing models, such as wild-type or transiently modified cells, is their stability and reproducibility. Unlike transient knockdown systems that may lead to variable expression levels, these knockout cell lines provide consistent and long-term gene disruption, ensuring reliable experimental outcomes.

Researchers and clinicians benefit significantly from the availability of these specialized cell lines, as they save time and resources while enhancing experimental accuracy. As experts in the field of genetic modification and cell culture, our company is dedicated to delivering high-quality biological products, ensuring that our customers have access to cutting-edge tools that enrich their scientific research and advance clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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