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CCDC6 Knockout Cell Lines

Gene: CCDC6

Official Full Name: coiled-coil domain containing 6provided by HGNC

Gene Summary: This gene encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the intracellular kinase-encoding domain of the ret proto-oncogene is the cause of thyroid papillary carcinoma.[provided by RefSeq, Sep 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04019 CCDC6 Knockout cell line (HeLa) Human CCDC6 1:3~1:6 Negative Online Inquiry
KO04020 CCDC6 Knockout cell line (HCT 116) Human CCDC6 1:2~1:4 Negative Online Inquiry
KO04021 CCDC6 Knockout cell line (HEK293) Human CCDC6 1:3~1:6 Negative Online Inquiry
KO04022 CCDC6 Knockout cell line (A549) Human CCDC6 1:3~1:4 Negative Online Inquiry

Background

CCDC6 Gene Knockout Cell Lines are genetically modified cell lines in which the CCDC6 gene has been disrupted or completely knocked out, providing a valuable tool for studying gene function and its implications in various biological processes and diseases. The mechanism underlying the knockout involves targeted genome editing techniques, such as CRISPR-Cas9 or TALENs, which introduce double-strand breaks at the specific locus of the CCDC6 gene, leading to subsequent loss of function due to error-prone repair processes.

These cell lines enable researchers to investigate the role of CCDC6 in cellular functions, including cell cycle regulation, apoptosis, and responses to oncogenic stress. Studying CCDC6 is particularly relevant in cancer biology, as its dysregulation has been associated with various tumors and malignancies, making these models instrumental in exploring therapeutic approaches targeting CCDC6-associated pathways.

One major advantage of CCDC6 Gene Knockout Cell Lines over alternative products is the precision of gene editing techniques that ensure specific deletion without off-target effects. They provide a robust platform for high-throughput screening of compounds that may restore normal function or inhibit the activities associated with CCDC6 dysregulation. As such, these cell lines are essential for drug discovery, biomarker identification, and understanding disease mechanisms, thereby accelerating translational research.

For researchers and clinicians, the availability of these specialized cell lines can dramatically enhance experimental rigor and reproducibility. Our company's commitment to providing high-quality, validated products reinforces the reliability of using CCDC6 gene knockout cell lines in research settings. By leveraging our extensive expertise in genetic engineering and cell biology, we ensure that your investigations into the CCDC6 gene will yield meaningful, applicable insights into cellular mechanisms and therapeutic interventions.

Please note that all services are for research use only. Not intended for any clinical use.

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