Gene: CBLN2
Official Full Name: cerebellin 2 precursorprovided by HGNC
Gene Summary: Predicted to be involved in maintenance of synapse structure and spontaneous synaptic transmission. Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be located in synaptic cleft. Predicted to be part of trans-synaptic protein complex. Predicted to be active in glutamatergic synapse. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23762 | CBLN2 Knockout cell line (HeLa) | Human | CBLN2 | 1:3~1:6 | Negative | Online Inquiry |
CBLN2 Gene Knockout Cell Lines are specialized cellular models that have been genetically engineered to facilitate the study of the CBLN2 gene, which is associated with synaptic function and neural signaling. By precisely knocking out the CBLN2 gene, these cell lines provide researchers with an invaluable tool to investigate the biological pathways involving this protein and its implications in neurodevelopmental and neuropsychiatric disorders.
The primary function of CBLN2 lies in its role as a signaling molecule that interacts with the glutamatergic system, playing a crucial role in synaptic adhesion and communication. By utilizing CBLN2 Gene Knockout Cell Lines, scientists can elucidate the molecular mechanisms that underlie synaptic plasticity and neurodevelopment through loss-of-function studies. This allows for an in-depth understanding of how perturbations in the CBLN2 gene may contribute to various neurological conditions, providing a platform for drug discovery and therapeutic interventions.
The scientific importance of these cell lines extends into both research and clinical applications. In research, they facilitate the exploration of gene function in real time, providing insights that could lead to breakthroughs in our understanding of cognitive disorders. In clinical settings, they serve as models for testing potential pharmacological agents aimed at modulating synaptic functions that might be impaired in CBLN2-related pathologies.
Compared to alternative gene editing techniques such as CRISPR-Cas9, CBLN2 Gene Knockout Cell Lines offer a streamlined approach that eliminates off-target effects and supports consistent, reproducible results. Their establishment uses robust methodologies ensuring the stability of the knockout mutations, making them reliable for long-term studies.
These cell lines are invaluable to researchers and clinicians dedicated to advancing the understanding of synaptic biology and developing targeted therapies for neurological disorders. By utilizing CBLN2 Gene Knockout Cell Lines, scientists can fast-track their research into actionable insights that improve patient outcomes.
At [Your Company Name], we pride ourselves on providing high-quality, innovative biological products that advance research and therapeutic developments. Our expertise in genetic engineering and cell line development ensures that our products meet the rigorous standards of the scientific community, helping researchers achieve their goals more effectively.
Please note that all services are for research use only. Not intended for any clinical use.
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