Gene: CAVIN3
Official Full Name: caveolae associated protein 3provided by HGNC
Gene Summary: The protein encoded by this gene was identified as a binding protein of the protein kinase C, delta (PRKCD). The expression of this gene in cultured cell lines is strongly induced by serum starvation. The expression of this protein was found to be down-regulated in various cancer cell lines, suggesting the possible tumor suppressor function of this protein. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30953 | CAVIN3 Knockout cell line (HeLa) | Human | CAVIN3 | 1:3~1:6 | Negative | Online Inquiry |
KO30954 | CAVIN3 Knockout cell line (HCT 116) | Human | CAVIN3 | 1:2~1:4 | Negative | Online Inquiry |
KO30955 | CAVIN3 Knockout cell line (A549) | Human | CAVIN3 | 1:3~1:4 | Negative | Online Inquiry |
CAVIN3 Gene Knockout Cell Lines are genetically engineered cell models devoid of the CAVIN3 gene, which is implicated in cellular processes such as lipid metabolism and muscle cell differentiation. These cells serve as powerful tools in both research and pharmaceutical development by allowing scientists to investigate the function of CAVIN3 in various biological contexts and pathways.
The primary function of CAVIN3 involves its role in caveolae formation, which are flask-shaped invaginations of the plasma membrane implicated in intracellular signaling and lipid homeostasis. By knocking out the CAVIN3 gene, researchers can elucidate the downstream effectors and regulatory networks affected by this gene, providing a clearer understanding of its involvement in metabolic disorders and cardiovascular diseases. The absence of CAVIN3 enables studies aiming to dissect the molecular mechanisms driving pathological conditions, offering insights that are critical for developing targeted therapies.
Scientific implications of CAVIN3 Gene Knockout Cell Lines extend to their applications in academic research as well as translational medicine. They serve as valuable models for drug discovery, toxicity assessments, and gene therapy studies, where the importance of understanding gene function and its interaction with therapeutic agents is crucial. These cell lines not only streamline the discovery processes but also improve the reliability and reproducibility of experimental results.
Compared to alternative cell lines, CAVIN3 Gene Knockout Cell Lines offer distinct advantages such as specific gene targeting, thereby reducing off-target effects that can occur with general knockdown methods like siRNA. Furthermore, these knockout lines can be maintained and cultured consistently, ensuring that results are both replicable and relevant.
For researchers and clinicians dedicated to unlocking the complexities of cellular biology and disease mechanisms, CAVIN3 Gene Knockout Cell Lines provide a high-value resource. They facilitate innovative research that can lead to the development of novel therapeutics aimed at metabolic dysfunction and related health issues. At [Your Company Name], we pride ourselves on our expertise in delivering high-quality, genetically modified cell lines that empower scientific discovery and enhance therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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