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CATSPER1 Knockout Cell Lines

Gene: CATSPER1

Official Full Name: cation channel sperm associated 1provided by HGNC

Gene Summary: Calcium ions play a primary role in the regulation of sperm motility. This gene belongs to a family of putative cation channels that are specific to spermatozoa and localize to the flagellum. The protein family features a single repeat with six membrane-spanning segments and a predicted calcium-selective pore region. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30453 CATSPER1 Knockout cell line (HeLa) Human CATSPER1 1:3~1:6 Negative Online Inquiry
KO30454 CATSPER1 Knockout cell line (HCT 116) Human CATSPER1 1:2~1:4 Negative Online Inquiry
KO30455 CATSPER1 Knockout cell line (A549) Human CATSPER1 1:3~1:4 Negative Online Inquiry

Background

CATSPER1 Gene Knockout Cell Lines are meticulously developed biological tools designed to facilitate research on the CATSPER1 gene, a key component in sperm motility and fertility. These cell lines have been genetically engineered through CRISPR-Cas9 technology to disrupt the CATSPER1 gene, enabling researchers to investigate the gene’s function and implications in reproductive biology.

The primary function of CATSPER1 is to encode a protein that forms part of the calcium-permeable ion channel in the sperm tail, crucial for sperm hyperactivation during fertilization. By providing a model system where the CATSPER1 gene is knocked out, these cell lines allow for in-depth studies into the molecular mechanisms governing sperm capacitation and the motility necessary for successful fertilization.

Scientifically, the implications of utilizing CATSPER1 Gene Knockout Cell Lines are substantial. Researchers can employ these models in investigations related to male infertility, development of contraceptive methods, and studies on sperm physiology. This product is particularly valuable in clinical settings where understanding sperm functionality can lead to enhanced diagnostics and therapeutic strategies for male fertility treatments.

Compared to alternatives, CATSPER1 Gene Knockout Cell Lines offer unparalleled specificity and reliability, decreasing experimental variability associated with other models. They are also easier to work with, as they provide consistent results, enabling more robust research outcomes. The precision of the knockouts ensures accurate reflection of the gene's biological role, positioning these cell lines as superior tools in scientific inquiry.

For researchers and clinicians focused on reproductive health, CATSPER1 Gene Knockout Cell Lines represent a critical asset. They grant direct access to study the implications of CATSPER1 in a controlled setting, allowing for valuable insights that can translate into improved reproductive health solutions.

Our company specializes in providing high-quality, rigorously validated biological products that empower scientists and clinicians alike. With a commitment to advancing research and healthcare, our offerings are designed to facilitate breakthrough discoveries in reproductive and cellular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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