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CASKIN1 Knockout Cell Lines

Gene: CASKIN1

Official Full Name: CASK interacting protein 1provided by HGNC

Gene Summary: Enables identical protein binding activity. Predicted to be involved in signal transduction. Predicted to be active in cytoplasm; glutamatergic synapse; and postsynapse. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20822 CASKIN1 Knockout cell line (HEK293) Human CASKIN1 1:3~1:6 Negative Online Inquiry

Background

CASKIN1 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to study the functional aspects of the CASKIN1 gene, which plays a crucial role in cellular signaling, cytoskeletal organization, and neuronal development. By employing CRISPR-Cas9 technology, these cell lines facilitate the targeted deletion of the CASKIN1 gene, allowing researchers to observe the resultant phenotypic changes and elucidate the gene's function more effectively.

The primary mechanism of action involves the introduction of guide RNA sequences that direct the Cas9 nuclease to the specific target region within the CASKIN1 gene, where it induces a double-strand break. This interruptive modification leads to either a frameshift mutation or a complete ablation of the gene, enabling comprehensive analyses of downstream signaling pathways and cellular responses that are dependent on CASKIN1 expression.

These knockout cell lines hold significant scientific importance as they are invaluable tools in biomedical research, particularly in the context of studying neurodevelopmental disorders where CASKIN1 may play a pivotal role. Furthermore, they provide a platform for examining the interactions between the CASKIN1 gene and other signaling pathways, bridging insights into both basic biology and potential therapeutic targets.

What sets CASKIN1 Gene Knockout Cell Lines apart from similar products is their high specificity, efficiency, and reproducibility in gene modification. Additionally, these cell lines are characterized by rigorous quality control measures, ensuring robust performance in various experimental setups. Their ready availability empowers researchers to design experiments with reduced lead time and increased certainty of outcomes.

For researchers and clinicians aiming to deepen their understanding of gene function in cellular contexts, the CASKIN1 Gene Knockout Cell Lines represent an essential resource. Their application in preclinical models can elucidate the mechanistic roles of CASKIN1, guiding future therapeutics development.

Our company specializes in producing high-quality biological tools that cater to the increasingly complex demands of modern biological research. By leveraging advanced genetic engineering techniques and a commitment to excellence, we ensure our products meet the highest standards of scientific rigor and effectiveness.

Please note that all services are for research use only. Not intended for any clinical use.

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