Gene: CAMSAP3
Official Full Name: calmodulin regulated spectrin associated protein family member 3provided by HGNC
Gene Summary: Enables actin filament binding activity and microtubule minus-end binding activity. Involved in several processes, including microtubule cytoskeleton organization; regulation of organelle organization; and zonula adherens maintenance. Located in cytoplasm; microtubule cytoskeleton; and zonula adherens. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19102 | CAMSAP3 Knockout cell line (HCT 116) | Human | CAMSAP3 | 1:2~1:4 | Negative | Online Inquiry |
KO19103 | CAMSAP3 Knockout cell line (HEK293) | Human | CAMSAP3 | 1:3~1:6 | Negative | Online Inquiry |
KO19104 | CAMSAP3 Knockout cell line (A549) | Human | CAMSAP3 | 1:3~1:4 | Negative | Online Inquiry |
CAMSAP3 Gene Knockout Cell Lines are specially engineered cell lines with the CAMSAP3 gene, a critical player in microtubule dynamics, entirely disrupted. This genetic manipulation allows researchers to study the role of CAMSAP3 in various cellular processes, including cell division, differentiation, and motility, without the confounding effects of its normal expression. By utilizing CRISPR/Cas9 technology, these knockout cell lines exhibit a complete lack of CAMSAP3 protein, enabling precise and targeted investigations into the consequences of its absence on microtubule organization and stability.
The primary function of CAMSAP3 is to stabilize microtubules at their minus ends, thereby influencing cellular architecture and transport processes. In the knockout cell lines, researchers can observe significant alterations in microtubule dynamics, providing valuable insights into how CAMSAP3-dependent mechanisms contribute to larger biological systems. With applications in cancer research, neurobiology, and developmental biology, these cell lines serve as vital tools for understanding diseases that are driven by microtubule dysfunction.
Compared to conventional cell lines, which may exhibit varied and unpredictable CAMSAP3 expression, our CAMSAP3 Gene Knockout Cell Lines offer unparalleled consistency and reproducibility in experimental outcomes. This homogeneity reduces experimental variability, increasing the reliability of research findings. Furthermore, the knockout model facilitates investigations into compensatory mechanisms, allowing scientists to elucidate pathways that may otherwise go unnoticed.
For researchers and clinicians looking to explore the intricate roles of microtubules in health and disease, CAMSAP3 Gene Knockout Cell Lines represent an invaluable resource, empowering studies that could lead to novel therapeutic targets and enhanced understanding of cellular biology. Our company specializes in providing high-quality, genetically modified cell lines, backed by a robust commitment to scientific innovation, ensuring that our products meet the highest standards for research excellence.
Please note that all services are for research use only. Not intended for any clinical use.
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