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C8orf34 Knockout Cell Lines

Gene: C8orf34

Official Full Name: chromosome 8 open reading frame 34provided by HGNC

Gene Summary: This gene encodes a protein that is related to the cyclic AMP dependent protein kinase regulators. Naturally occurring mutations in this gene are associated with an increased risk for severe toxicities, such as diarrhea and neutropenia, in patients undergoing chemotherapeutic treatment. [provided by RefSeq, Mar 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30529 C8orf34 Knockout cell line (HEK293) Human C8orf34 1:3~1:6 Negative Online Inquiry

Background

C8orf34 Gene Knockout Cell Lines are specially engineered cell lines created through advanced genetic editing techniques to specifically disrupt the C8orf34 gene. This gene is implicated in various biological processes, including the regulation of cellular metabolism and immune response, making these knockout cell lines an invaluable tool for researchers aiming to unravel complex biological pathways.

The primary function of C8orf34 Gene Knockout Cell Lines is to enable scientists to study the effects of the absence of the C8orf34 protein in cellular contexts. Utilizing CRISPR-Cas9 technology, these cells exhibit a precise knockout, allowing for the investigation of phenotype changes, metabolic alterations, and protein-protein interactions that could be influenced by C8orf34. These knockout cell lines serve as critical models for dissecting the gene’s role in disease mechanisms, particularly in cancer and autoimmune disorders, where dysregulation of immune responses can lead to pathological conditions.

Scientifically, the C8orf34 Gene Knockout Cell Lines are of great importance in both basic research and clinical studies. They facilitate high-throughput screening of therapeutics targeting metabolic pathways, contribute to understanding the gene's contribution to pathology, and provide a basis for developing targeted therapies. Furthermore, they can also be pivotal in drug discovery and testing, allowing researchers to identify novel therapeutic targets and assess the efficacy of experimental drugs.

Compared to alternative models, such as transient transfection or overexpression systems, these knockout cell lines offer enhanced stability and reproducibility in experimental results. This guarantees that findings are reflective of the effects of gene knockout rather than temporary changes in gene expression.

By incorporating C8orf34 Gene Knockout Cell Lines into your research, you gain access to a powerful and innovative tool that can propel discoveries forward. The capacity to create high-fidelity models of gene function equips researchers and clinicians alike with deeper insights into biological mechanisms, fortifying path toward therapeutic breakthroughs.

Our company specializes in providing top-tier biological products, and we are committed to empowering the scientific community with precise, reliable tools for modern research, ensuring our offerings meet the highest standards for efficacy and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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