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C3orf33 Knockout Cell Lines

Gene: C3orf33

Official Full Name: chromosome 3 open reading frame 33provided by HGNC

Gene Summary: Involved in negative regulation of ERK1 and ERK2 cascade and regulation of DNA-binding transcription factor activity. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19282 C3orf33 Knockout cell line (HeLa) Human C3orf33 1:3~1:6 Negative Online Inquiry
KO19283 C3orf33 Knockout cell line (HCT 116) Human C3orf33 1:2~1:4 Negative Online Inquiry
KO19284 C3orf33 Knockout cell line (HEK293) Human C3orf33 1:3~1:6 Negative Online Inquiry
KO19285 C3orf33 Knockout cell line (A549) Human C3orf33 1:3~1:4 Negative Online Inquiry

Background

C3orf33 Gene Knockout Cell Lines are highly specialized biological tools designed to facilitate the study of the C3orf33 gene, which has been implicated in various cellular processes and associated with certain pathologies. These engineered cell lines are created through a precise gene-editing technique, specifically CRISPR-Cas9 or similar methodologies, to completely disrupt the C3orf33 gene’s expression. This results in a loss-of-function model that can be utilized to uncover the functional roles of C3orf33, enabling researchers to explore its impact on cellular behavior, signaling pathways, and disease mechanisms.

The primary mechanism of action involves the introduction of targeted mutations to the gene sequences, leading to the absence of functional protein. This allows for in-depth analysis of phenotypic changes that occur in response to the knockout. Researchers can employ these cell lines in various applications, including drug discovery, functional genomics, and the study of genetic disorders, thereby contributing valuable insights into potential therapeutic targets.

The scientific importance of C3orf33 Gene Knockout Cell Lines cannot be overstated, as they serve as critical tools in both basic research and translational science. Their unique ability to offer a controlled environment for dissecting gene function supports advancements in understanding the molecular underpinnings of diseases such as cancer and neurodegenerative disorders.

In comparison with traditional cell line models or other gene editing systems, C3orf33 Gene Knockout Cell Lines not only provide a more efficient means of achieving precise gene disruption but also minimize off-target effects, enhancing experimental reliability. Their design is optimized for high reproducibility, allowing for consistent results across different laboratories.

For researchers and clinicians focusing on genetic studies, these knockout cell lines represent a crucial resource that aids in elucidating complex biological systems. By choosing our C3orf33 Gene Knockout Cell Lines, users gain access to a product backed by our extensive expertise in genomic technologies and commitment to advancing biological research. Our leading-edge solutions facilitate critical breakthroughs in understanding and addressing multifaceted health challenges.

Please note that all services are for research use only. Not intended for any clinical use.

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